septicemia

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septicemia

septicemia (sĕptĭsēˈmēə), invasion of the bloodstream by virulent bacteria that multiply and discharge their toxic products. The disorder, which is serious and sometimes fatal, is commonly known as blood poisoning. The invasive organisms are usually streptococci or staphylococci but may be any type of bacteria. Septicemia occurs most often in older people who have underlying disease that makes them more susceptible to the infection. The primary causes of septicemia are infection within the walls of the blood vessels, rapidly progressing tissue infections (osteomyelitis, cellulitis), virulent systemic disease (meningitis, typhoid), and local infections (abscess, carbuncle) that the defense mechanisms of the body are unable to contain. The microorganisms usually spread to other organs, such as the lungs, liver, and brain.

Symptoms of septicemia are fever (usually quite high), chills, low blood pressure, confusion, and rash; it often results in multiple organ failure if not treated promptly with antibiotics. The diagnosis can be confirmed with blood cultures for the organism or with blood tests for antibodies or high levels of white blood cells.

See also toxemia; toxic shock syndrome.

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septicemia

[‚sep·tə′sē·mē·ə]
(medicine)
A clinical syndrome in which infection is disseminated through the body in the bloodstream. Also known as blood poisoning.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.

septicaemia

(US), septicemia
a condition caused by pus-forming microorganisms in the blood
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005