Neutrophil

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neutrophil

[′nü·trə‚fil]
(histology)
A large granular leukocyte with a highly variable nucleus, consisting of three to five lobes, and cytoplasmic granules which stain with neutral dyes and eosin.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Neutrophil

 

(also called polymorphonuclear neutrophil leukocyte, microphage), a type of white blood cell, or leukocyte, occurring in vertebrates and man. The diameter of a neutrophil ranges from 9 to 12 μ. The cytoplasm of these cells contains granules that attract both basic and acidic dyes, and this is why these leukocytes are called neutrophils.

A neutrophil is classified according to its degree of maturity: a metamyelocyte is a young neutrophil with an unsegmented nucleus, a rod neutrophil has a nucleus in the shape of a curved rod, and segmented, or filamented, neutrophils have segmented nuclei. Neutrophils are phagocytes that are capable of ingesting small foreign particles, including microbes. By elaborating hydrolytic enzymes, neutrophils can lyse dead tissue. Neutrophilia is an abnormal increase in the concentration of neutrophils in the blood. (SeeLEUKOCYTOSIS.)

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Parameter (International Systems of Mean SD Median Units) Erythrocytes (x[10.sup.12]/L) 5.65 0.97 5.75 PCV 0.39 0.31 0.39 Hemoglobin (g/L) 121.00 13.00 121.00 Mean corpuscular volume (fL) 69.70 10.00 68.10 Mean corpuscular hemoglobin 31.40 2.20 31.40 concentration (%) Leucocytes (x [10.sup.9]/L) 9.70 3.88 8.67 Band neutrophils (x [10.sup.9]/L) 7.57 0.11 0.00 Segmented neutrophils (x [10.sup.9]/L) 4.93 3.24 4.04 Eosinophils (x [10.sup.9]/L) 0.21 0.33 0.09 Basophils (x [10.sup.9]/L) 0.01 0.03 0.00 Lymphocytes (x [10.sup.9]/L) 4.08 2.23 3.456 Monocytes (x [10.sup.9]/L) 0.46 0.87 0.27 Platelets (x [10.sup.9]/L) 270.72 52.12 268.60 Parameter (International Systems of Min.-Max.
Within 1 week after receiving doxycycline, the patient's symptoms and hematologic abnormalities had resolved (neutrophil count 4,378 cells/[micro]L, no band neutrophils, and platelet count of 320,000/[micro]L).
The elevated white blood cell count, elevated erythrocyte sedimentation rate, increased presence of band neutrophils, elevated concentrations of neutrophils and the increased concentration of acute phase proteins demonstrate this immune response.
Cells were pre-classified into: band neutrophils, segmented neutrophils, lymphocytes, monocytes, eosinophils, basophils, metamyelocytes, myelocytes, promyelocytes, blast cells, lymphocyte variant forms and plasma cells.
On the following day, laboratory studies revealed leukopenia with lymphocytosis and absence of band neutrophils, thrombocytopenia, decreased erythrocyte sedimentation rates (ESR), hyperbilirubinemia, mostly due to an increase in direct bilirubin, a large increase in liver enzymes levels, and anti-HIV serology and dengue fever antigen both negative.
There are 5 types of WBCs, each with different functions, that make up the differential: neutrophils (band neutrophils and segmented neutrophils), monocytes, lymphocytes, eosinophils, and basophils.
The white blood cell differential revealed the following values: 0.63 segmented neutrophils; 0.02 band neutrophils; 0.13 lymphocytes; 0.15 monocytes; 0.02 basophils; 0.03 myelocytes; and 0.02 metamyelocytes.