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A large granular leukocyte with a highly variable nucleus, consisting of three to five lobes, and cytoplasmic granules which stain with neutral dyes and eosin.



(also called polymorphonuclear neutrophil leukocyte, microphage), a type of white blood cell, or leukocyte, occurring in vertebrates and man. The diameter of a neutrophil ranges from 9 to 12 μ. The cytoplasm of these cells contains granules that attract both basic and acidic dyes, and this is why these leukocytes are called neutrophils.

A neutrophil is classified according to its degree of maturity: a metamyelocyte is a young neutrophil with an unsegmented nucleus, a rod neutrophil has a nucleus in the shape of a curved rod, and segmented, or filamented, neutrophils have segmented nuclei. Neutrophils are phagocytes that are capable of ingesting small foreign particles, including microbes. By elaborating hydrolytic enzymes, neutrophils can lyse dead tissue. Neutrophilia is an abnormal increase in the concentration of neutrophils in the blood. (SeeLEUKOCYTOSIS.)

References in periodicals archive ?
Though increased presence of band neutrophils may be seen in a variety of diseases such as bacterial and viral infections, inflammatory processes, neoplasms, and other diseases, the WBC and the absolute neutrophil count may serve as a better diagnostic tool.
The patient's neutrophil count (2,553 cells/[micro]L) was within low reference limits, accompanied by 5% band neutrophils, and mild thrombocytopenia (148,000 platelets/[micro]L).
The elevated white blood cell count, elevated erythrocyte sedimentation rate, increased presence of band neutrophils, elevated concentrations of neutrophils and the increased concentration of acute phase proteins demonstrate this immune response.
Cells were pre-classified into: band neutrophils, segmented neutrophils, lymphocytes, monocytes, eosinophils, basophils, metamyelocytes, myelocytes, promyelocytes, blast cells, lymphocyte variant forms and plasma cells.