barbituric acid


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barbituric acid

a white crystalline solid used in the preparation of barbiturate drugs. Formula: C4H4N2O3

barbituric acid

[¦bär·bə¦tu̇r·ik ′as·əd]
(organic chemistry)
C4H4O3N22,4,6-Trioxypyrimidine, the parent compound of the barbiturates; colorless crystals melting at 245°C, slightly soluble in water.
References in periodicals archive ?
max], of the chromophore derived from cotinine) for 280-[micro]L aliquots of acetone/water (5:9 by vol) in place of the potassium cyanide, Chloramine-T, and barbituric acid reagents.
One possible reason for their disappointing results may have been that they measured absorbance at 490 nm (with blank correction at 630 nm) instead of at ~508 nm, the absorption maximum for the chromophores derived from cotinine and other nicotine metabolites when barbituric acid is used as the condensing reagent.
The isothermal polymerizations of N, N' -bismaleimide-4, 4'-diphenylmethane (BMI) with barbituric acid (BTA) with BTA/BMI = 1/2 (mol [mol.
Some barbituric acid derivatives also show immuno-modulating activity and can act as nitric oxide scavenger [11].
R= Barbituric acid 2-8 and Thiobarbituric acid 9-15.
Recently, barbituric acid derivatives have als o received great interes t for applications in Nanos cience [17, 18]
Barbituric acid and its derivatives demonstrated important biological activities such as, hypotensive and tranquilizers [2].
The first barbituric acid was synthesized in 1864 by Adolph von Baeyer [7].
Summary: A convenient one pot green chemistry route has been developed for the synthesis of 5-arylidenebarbiturates by way of an acetic acid catalyzed Knoevenagel condensation of a variety of aromatic aldehydes with barbituric acid.
Merk), barbituric acid, (BDH), atenolol, (Zafa) pentazocine (Searle Pak.