Treatment with two different doses of sonidegib in patients with locally advanced or metastatic
basal cell carcinoma (BOLT): a multi-centre, randomised, double-blind phase 2 trial.
- The approved drugs in the
basal cell carcinoma space target the immune system, thymidylate synthase, and hedgehog signaling pathway.
Variations of
basal cell carcinomas according to gender, age, location and histopathological subtype.
Surgical excision versus Mohs micrographic surgery for primary and recur- rent
basal cell carcinoma of the face: a prospective, randomized controlled trial with 5 years follow-up.
In our study,
basal cell carcinoma was the most frequent lesion, followed by squamous cell carcinoma.
Founded by specialists in hedgehog pathway signaling, PellePharm, a BridgeBio company, is committed to targeting rare, genetic dermatological diseases, including Gorlin Syndrome and High Frequency
Basal Cell Carcinoma, at their source.
The objective of the study is to analyse the different histopathological patterns of
Basal Cell Carcinoma (BCC) in 30 consecutive cases of
basal cell carcinoma.
The etiology of the collision between
basal cell carcinoma and melanoma remains unknown.
His father and paternal grandmother had a positive history of odontogenic cysts as well as
basal cell carcinomas, although the family history of OKCs was negative.
We performed biopsies from the lesion on the left forearm, the axillary ulcers, and the papules on the thoracic wall with the histopathological finding of a
basal cell carcinoma (BCC) in all lesions.
Although these cancers rarely metastasize,
basal cell carcinoma can invade nearby structures.
These findings indicate that histogenetically the origin cell of BCC is from the
basal cell of epidermis, located at the interfollicular epidermis and infundibulum of the hair follicle distributed along the basal layer, supporting the theories that the origin of BCC arises from the
basal cell layer of the interfollicular epidermis [8, 27], not the ORS and hair follicles [15, 28].
