basement membrane

(redirected from basement membrane zone)
Also found in: Dictionary, Medical, Acronyms.
Related to basement membrane zone: basal lamina

basement membrane

[′bās·mənt ′mem‚brān]
(histology)
A delicate connective-tissue layer underlying the epithelium of many organs.
References in periodicals archive ?
It is characterized by tissue-bound autoreactive antibodies against structural proteins of the basement membrane zone and of hemidesmosomes that mediate the recruitment of inflammatory and immune cells with the generation of chronic inflammation.
Biopsy of the blister showed linear deposits of IgG and C3 at the basement membrane zone. DCP was started, his lesions cleared in one month (phase I).
Direct immunofluorescence microscopic examination of perilesional tissue showed linear deposits of IgA at the basement membrane zone (Figure 6).
Skin lesions in DH are histologically characterized by neutrophilic infiltrates leading to destruction of basement membrane zone (BMZ) proteins and anchoring fibers and blister formation [4-6].
Direct immunofluorescence of perilesional mucosa reveals linear deposits of IgG and complement in the subepidermal basement membrane zone. (2)
Direct immunofluorescence of healthy skin will show a typical granular IgA deposition in the dermal papillae; some lesions will show a linear deposition of granular IgA in the basement membrane zone.
Thickening of basement membrane zone was observed in systemic lupus erythematosus specimen which was concurrent to findings of Alahlafi AM et al.
Immunofluorescence study has failed to demonstrate any immunoglobulin or fibrin deposits along basement membrane zone.4
Skin lesions in DH are histologically characterized by neutrophilic infiltrate leading to destruction of basement membrane zone (BMZ) proteins, anchoring fibers, and blister formation [4-6].