basement membrane

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basement membrane

[′bās·mənt ′mem‚brān]
(histology)
A delicate connective-tissue layer underlying the epithelium of many organs.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
ECM components conserved from sponges to humans include three clades of fibrillar collagens and basement membrane collagen IV [7].
Although the exact etiology of PED is unknown, it is evident that any disorder that can destabilize the complex attachment of the basement membrane of the RPE and Bruch membrane will have an effect on PED [1, 3].
Ninomiya, "Differential expression of type IV collagen isoforms, a5(IV) and a6(IV) chains, in basement membranes surrounding smooth muscle cells," Histochemistry and Cell Biology, vol.
Goodpasture's syndrome (GPS) is a rare and life threatening autoimmune condition with autoantibodies directed against the glomerular basement membrane (GBM) antigen.
Amnion has shown an ability to form an early physiologic "seal" with the host tissue precluding bacterial contamination and multiple studies support amnion's ability to decrease the host immunologic response via mechanisms such as localized suppression of polymorphonuclear cell migration.Data suggests that the amnion basement membrane closely mimics the basement membrane of human oral mucosa.
In the classical view, MMPs are collectively capable of degrading all components of the ECM and basement membrane, restricting their functions to tissue remodeling and maintenance; they are now recognized as being responsible for mediating crucial functions in a variety of processes, particularly related to immunity and repair, such as cell migration, leukocyte activation, antimicrobial defense, and chemokine processing.
The reason for this is the increased permeability of Glomerular Basement Membrane (GBM), thus an indication of some degree of renal failure.
The glands are widely spaced and surrounded by thick eosinophilic basement membranes. (8) other histological features described in REAH include stromal edema with inflammatory cell infiltrates, polypoidal growth, seromucinous gland proliferations, vascular and fibroblastic proliferations.
In this disease, there is formation and deposition of antibodies against the alpha-3 chain of type IV collagen along glomerular and alveolar basement membranes.
Bromide ions, negatively charged versions of bromine, stabilize cellular support structures called basement membranes, Hudson's team discovered.