The cytoplasm was strongly basophilic
. Very few follicle cells were visible around the oocytes (Fig.
(B) Numerous blastoconidia are observed in the middle of the pulmonary parenchyma, with a slightly basophilic
central cell, surrounded by an unstained capsule.
Hematoxylin binds to basophilic
substances and they are dyed violet-blue (such as heterochromatin and ribosomal RNA, which are acidic and negatively charged); eosin binds to acidophilic substances with positive charge and they are dyed pink or orange (such as cationic amino acids and proteins).
Bone marrow morphologic findings at the time of B-lymphoblastic leukemia/lymphoma diagnosis : blasts comprised 80% of the bone marrow aspirate nucleated cells and consisted of medium-sized cells with high nuclear-to-cytoplasmic ratio, mild nuclear irregularities, coarsely dispersed chromatin, inconspicuous nucleoli, and small to moderate amount of deeply basophilic
cytoplasm with occasional vacuoles.
Their nuclei are twice bigger than small lymphocytes, nucleoli are prominent and the cytoplasm is basophilic
Histopathological examination of hematoxylin and eosin stained sections revealed an encapsulated tissue (figure 4) composed of numerous serous acinar cells with abundant granular basophilic
cytoplasm and round darkly stained eccentrically placed nucleus with multiple vacuolated cyst-like spaces (figure 5).
(3) Histologic findings of proliferative myositis include two primary features: infiltration of the muscle with large basophilic
giant cells that resemble ganglion cells and proliferative fibroblasts primarily affecting the interfascicular connective tissue.
Characteristic microscopic findings in hyperostosis included the development of new bone tissue, which appeared as marked thickening of the trabecular structures in the zone, and correspondingly, the narrowing of centrally located bone marrow spaces replaced by a highly vascular fbrous tissue and the presence of prominent basophilic
cement lines between these thick, newly formed trabeculae and the mature bone tissue (McConnell et al., 2006; Thompson et al., 2011).
Cells of submucosal Brunner's glands showed nucleomegaly with eosinophilic intranuclear and basophilic
cytoplasmic CMV inclusions (Figure 1(b)).
Decreased villous vascularity and basophilic
stippling in the basement membrane has also been observed .
Laboratory findings showed microcytic anemia, without signs of iron deficiency or thalassemia; basophilic
stippling of red blood cells; mild leukocytosis; and increased liver enzyme activities (Table 1, case 2).
cells were often located in the peripheral area, whereas pale basophilic
cells were located in the central area (Figure 2).