Scientists at the Salk Institute for Biological Studies now report discovering that ES cells cycle in and out of a "magical state" in the early stages of embryo development, during which a battery of genes
essential for cell potency (the ability of a generic cell to differentiate, or develop, into a cell with specialized functions) is activated.
The research identifies for the first time that DUO1 switches on a battery of genes that together govern sperm cell production and their ability to produce seeds.
The discovery of a battery of genes governed by DUO1 has shed light on the mechanisms by which plants control sperm cell formation and fertility.
Parallel to these fundamental revelations were the observations that all organisms are equipped with a battery of genes
that produce proteins whose primary roles are to prevent or repair chemical and physical damage to DNA; such activities protect against mutation and cell death induced by DNA-damaging agents, and studies of these activities eventually evolved into the field of genetic toxicology.
In conclusion, calibrated RT-PCR is a reliable and accurate method for evaluating the expression of AHR and a related battery of genes
that have been proposed as mediators of the majority of biochemical and toxicologic effects of several xenobiotics.