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(hī'pərplā`zhə): see hypertrophyhypertrophy
, enlargement of a tissue or organ of the body resulting from an increase in the size of its cells. Such growth accompanies an increase in the functioning of the tissue. In normal physiology the growth in size of muscles (e.g.
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The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



an increase in the number of structural elements of tissues or organs. In man and animals, hyperplasia is based on the intensified reproduction of cells and the formation of new structures. Hyperplasia is observed in various types of pathological growth of tissues (chronic productive inflammation and tumor), in regeneration, and in hypertrophy. Hyperplasia often carries with it compensating characters. In plants, it may be a local growth of tissues resulting from mitotic or amitotic cell division. It occurs with infection by destructive or pathogenic organisms, during trauma, and under the influence of growth stimulants, pesticides, and other preparations. The result of hyperplasia is the formation of galls, calluses, and warts.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.


Increase in cell number causing an increase in the size of a tissue or organ.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Efficacy and safety of photoselective vaporization of the prostate with 120 W 532 nm laser in patients with benign prostatic hyperplasia on anticoagulation or antiplatelet therapy: Observations on long-term outcomes.
Risk factors for lower urinary tract symptoms suggestive of benign prostatic hyperplasia in a community based population of healthy aging men: the Krimpen Study.
Bladder dysfunction in patients with benign prostatic hyperplasia: Relevance of cystometry as prognostic indicator of the outcome after prostatectomy.
Da Motta Leal Filho et al., "Prostatic artery embolization as a primary treatment for benign prostatic hyperplasia: Preliminary results in two patients," CardioVascular and Interventional Radiology, vol.
Comparison with Other Studies Benign Prostatic Hyperplasia PSA Range ng/mL Present Kshitij Eshtiaq Prabhat (15) Study et al (13) Ali (14) 0-4 60.9% 71.6 -- -- 4-10 23.7 % 22.6 85 87.6 >10 15.2 % 3.0 15 12.4 Carcinoma Prostate PSA Range ng/mL Kshitij Mwaaykoma Sladana Prabhat Present et al (13) (16) (17) (15) study 0-4 10.5 -- 2.5 -- -- 4-10 23.6 5.3 27.50 14.9 11.6 >10 63.7 94.7 70.0 74.2 88.3
Treatment of benign prostatic hyperplasia and lower urinary tract symptoms with continuous low dose of sildenafil seems to be a good treatment choice in the patients with mild to moderate benign prostatic hyperplasia and lower urinary tract symptoms, especially in those patients with concomitant erectile dysfunction.
Between July 2015 and December 2015, a total of 53 patients with primary symptom (urinary retention) of benign prostatic hyperplasia were included in this stu-dy.
* The report provides a snapshot of the global therapeutic landscape of Benign Prostatic Hyperplasia
2010 Update: Guidelines for the management of benign prostatic hyperplasia. Can Urol Assoc J 2010;4:310-6.
Research on the use of pulsed electromagnetic field therapy in dogs with benign prostatic hyperplasia (BPH), also known as enlarged prostate, suggests it may hold promise for the nonsurgical treatment in men.

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