benzamide


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Related to benzamide: benzanilide

benzamide

[ben′za‚mīd]
(organic chemistry)
C6H5CONH2 A compound with melting point 132.5° to 133.5°C; slightly soluble in water, soluble in ethyl alcohol and carbon tetrachloride; used in chemical synthesis.
References in periodicals archive ?
Keywords: Design, Synthesis, Fluopicolide, Benzamide derivatives, Antifungal activity.
On the basis of chemical structures and enzymatic activities, HDACIs are (Figure 3) (10) chemically classified as hydroxamates (vorinostat, panobinostat, givinostat, quisinostat, abexinostat, belinostat, tefinostat, resminostat, pracinostat), benzamides (entinostat, mocetinostat, chidamide), aliphatic acids (valproic acid), and cyclic peptides (romidepsin).
In the direction of search the scope of this 3-CR, some substituted benzaldehydes reacted with amides (benzamide, urea, acetamide)/thiourea (2a-d) and 2-naphthol (3) under the optimized reaction conditions, and the results are shown in Table 2.
Performance of a similar product (N,N diethyl Benzamide) in a different formulation was also reported elsewhere [4] in India, in which, when applied at 10mg/cm2, the percentage protection was 100% against Anopheline with average protection time of 11 hrs and it was 98.8% against Cx.
Roberts, "The pharmacological basis of the therapeutic activity of clebopride and related substituted benzamides," Current Therapeutic Research, vol.
The six peaks position at 530.50-530.69 eV (O=U=O) [33, 34], 531.40-531.55 eV (C-O-U), 532.20-532.33 eV (C=O of [beta]-diketonate), 532.60-532.80 eV (C-O-C), 533.40-533.50 eV (C=O of benzamide), and 533.90-534.00 eV (adsorbed [H.sub.2]O) [35] was observed.
Clebopride, a nonselective benzamide, also has high affinity for D2, D3, and D4 receptors [2]; thus, it acts as a dopamine receptor-blocking agent.
MS-275** Entinostat, also known as SNDX-275 and MS-275, is a benzamide histone deacetylase inhibitor undergoing clinical trials for treatment of various cancers.
** deet (diethylmethyl benzamide); AI3-37220 (1-(3-cyclohexen1-cabonyl)-2-m ethyl piperidine); CIC-4 (2-hydroxomethylcyclohexl) acetic acid)
HBI-8000 is a member of the benzamide class of histone deacetylase (HDAC) inhibitors designed to block the catalytic pocket of Class I HDACs.
Label precusors are then attached to the benzamide groups and reacted to form the desired label compounds.