benzothiazole


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benzothiazole

[¦ben·zō′thī·ə‚zȯl]
(organic chemistry)
C6H4SCHN A thiazole fused to a benzene ring; can be made by ring closure from o-amino thiophenols and acid chlorides; derivatives are important industrial products.
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Allam, Synthesis of some new benzothiazole derivatives as potential antimicrobial and antiparasitic agents.
Several rest breaking compounds have been tested over the last decades, such as mineral oil, calcium cyanamide, potassium nitrate, hydrogen cyanamide, dinitro-orthocresol (DNOC), dinitro-ortho-butyl-phenol (DNOPB), dinitro-butylphenol (DNBP), thiourea, sodium pentachlorophenate, TCMTB (2-thiocyanomethylthio), benzothiazole (30%), thiadizuron (TDZ), gibberellic acid (PETRI et al, 2014; SAGREDO et al., 2005), Erger[R], and calcium nitrate (HAWERROTH et al., 2010).
Methoxypropylamine also reacts with carbamates, quinones, benzothiazole and other substrates to obtain similar products.
Synthesis of benzothiazole derivatives and study of their anti-fungal activities.
To the mixture of the s-alkylated 2-mercapto benzothiazole (compound-2) (1.0 mmol) obtained from the above mentioned step dissolved in absolute ethanol (20 ml), added hydrazine hydrate (80%, 3.2 mmol), and then reflux the reaction mixture with continuous stirring for 11-12 h.
2-Amino benzothiazole derivatives have received considerable attention owing to their unique structures and exquisite pharmacophores observed in many diagnostic and therapeutic agents.
[6] achieved an incomplete TCMTB degradation (75%) in an anaerobic and aerobic wastewater treatment pilot plant, yielding mercaptobenzothiazole (MTB), benzothiazole (BT), and hydroxybenzotriazole (OHBT) as the degradation products, which however are harmful compounds that cause dermatitis [7], cell apoptosis [8], and respiratory tract irritation [9], respectively.
Kimura et al., "[sup.18]F-Labeled phenyldiazenyl benzothiazole for in vivo imaging of neurofibrillary tangles in alzheimer's disease brains," ACS Medicinal Chemistry Letters, vol.
Kucukbay and Durmaz [19] assessed 40 organic or organometallic derivatives of benzimidazole and benzothiazole and 5 rhodium (I) and ruthenium (II) complexes for their in vitro antifungal activity against C.
Compound (22) bears a sulfonyl moiety in place of L2 and has a distinct highly lipophilic tail of benzothiazole, which was moderately antidiabetic.