Comparison of the efficacy and safety of a combination topical gel formulation of benzoyl peroxide
and clindamycin with benzoyl peroxide
, clindamycin and vehicle gel in the treatment of acne vulgaris.
Those fabricators who employ the CV (continuous steam vulcanization) system and who find it feasible to use benzoyl peroxide
, DiCup; Varox, rather than bis (2,4 dichlorobenzoyl) peroxide will realize the following advantages:
In contrast, the benzoyl peroxide
cleanser had minimal effect on the reduction of P.
: Benzoyl peroxide
is a powerful antimicrobial agent (32) destroying both surface and ductal bacterial organisms and yeasts.
One of the newer topicals combines benzoyl peroxide
and a retinoid stable in its presence, adapalene.
Micronized benzoyl peroxide
is said to penetrate deeply into pores to reduce blemishes, eliminate acne-causing bacteria and unclog pores.
According to agency policy, benzoyl peroxide
is now GRASE (generally recognized as safe and effective).
Dab on a bit of benzoyl peroxide
cream either way, and hope for the best.
For moderate comedonal and mild to moderate papulopustular acne, combination therapy with either benzoyl peroxide
or topical retinoids (adapalene [Differin], tazarotene [Tazorac], tretinoin [Retin-A]) plus topical antibiotics (erythromycin or clindamycin) is proven most effective (SOR: A).
Azelaic acid cream plus benzoyl peroxide
gel is a cost-effective alternative to benzoyl peroxide
/ erythromycin gel for acne treatment, Dr.
Two effective zit-zappers in anti-acne products: salicylic acid, which helps unblock pores, and benzoyl peroxide
, an antiseptic that dries out pimples and keeps infection-causing bacteria under control.
On a relative scale, Di-t-butyl peroxide is a relatively unreactive material while benzoyl peroxide
is quite reactive.