is prevailing active medicinal agent.
amurense is berberine
. In this study, the extract of P.
Xiang, "Effect of jatrorrhizine, berberine
, Huanglian Decoction and compound-mimic prescription on blood glucose in mice," Chinese Traditional & Herbal Drugs, vol.
and dimethyl sulfoxide (DMSO) were obtained from SigmaAldrich Chemical Inc.
Zhao et al., "Effect of berberine
on acetylcholine-induced atrial fibrillation in rabbit," American Journal of Translational Research, vol.
, one of the major alkaloids isolated from C.
is a quaternary plant ammonium salt extract, which has lipid-lowering, hypoglycaemic, anti-inflammatory and antihypertensive effects, beyond a low systemic bioavailability (Cicero and Ertek 2009).
A study published in the Asian Pacific Journal of Tropical Medicine reports that in lab tests, berberine
(the active compound in the plant) was added to drug-resistant E.
Organically cultivated goldenseal, as well as Oregon grape root (Mahonia spp.) and barberry (Berberis spp.), all contain "berberine
," an alkaloid that has potent antimicrobial activity on contact, such as when rinsing with a neti pot.
This plant is rich in medicinally important phytochemical constituents like berberine
(Ali and Khan, 1978), umbellatine (Baquar, 1989), plamitine (Gosh et al., 1990), baluchistanamine, karakoramine, gilgitine, jhelumine, punjabine, sindamine, chinabine (Manske, 1998), berbamine (Khare, 2004), [beta]-sitosterol, 4-4,dimethylhexadeca-3-ol, Butyl-3-hydroxypropylphthalate, 3-(4'-(6-methylbutyl) phenyl) propan-1-ol (Sabir et al., 2013).
, an orangish-yellow alkaloid found at high levels in the bark and root structures of plants including Oregon grape (Mahonia aquifolium), goldenseal (Hydrastis canadensis), barberry (Berberis vulgaris), and Chinese goldthread (Coptis chinensis), has a broad and wide history of use.