lactam

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Related to beta-lactam: beta-lactamase, Beta-lactam Ring

lactam

[′lak‚tam]
(organic chemistry)
An internal (cyclic) amide formed by heating gamma (γ) and delta (δ) amino acids; thus γ-aminobutyric acid readily forms γ-butyrolactam (pyrrolidone); many lactams have physiological activity.
References in periodicals archive ?
Hahn and colleagues suspect that patients who often don't achieve therapeutic blood levels of antibiotics may be genetically predisposed to metabolize beta-lactam antibiotics quickly.
In accordance with recommendations and guidance received from the FDA, the company expects the Phase 3 trial to comprise a global, event-driven clinical trial with a fixed maximum number of patients for total enrollment, and to include separate co-primary endpoints designed to evaluate the efficacy and safety of ribaxamase in a patient population being treated with a representative selection of intravenous beta-lactam antibiotics.
We conducted a 6-month retrospective record review to determine whether there is bacterial culture data to support our initial empiric gram-negative double coverage with extended antipseudomonal beta-lactam (piperacillin-tazobactam) and fluoroquinolones (ciprofloxacin and levofloxacin) in our military hospital patient population.
The hospital's EHR system generated a daily list of patients with a history of penicillin allergy who were on second-line options--vancomycin, daptomycin, aztreonam, linezolid, or moxifloxacin--for infections that would be better treated with beta-lactam antibiotics.
MRSA and related resistant bacteria can withstand a group of antibiotics called beta-lactams, which includes penicillin and methicillin.
A recent study looked at whether additional community-associated MRSA coverage with trimethoprim-sulfamethoxazole in addition to beta-lactam therapy for cellulitis showed any benefit over therapy with only a beta-lactam (Clin.
The MaxSignal Beta-Lactam ELISA Test Kit was developed to ease these concerns and assure that food is free of beta-lactam antibiotic residues.
Analysis of twelve beta-lactam antibiotics in human plasma by HPLC with ultraviolet detection.
Beta-lactamase inhibitors restore or potentiate the activity of beta-lactam antibiotics.
Use of different screening test for beta lactam residues by laboratories, milk collectors and processing plants in Bosnia and Herzegovina during 2010 Snap Beta-lactam test 50% Charm MLR ROSA Beta-lactam test 30% Inhibition MRL BRT test 12% Other test 8% Note: Table made from pie chart.
and Enterome Bioscience SA have entered into an agreement to conduct metagenomic research on the effects of beta-lactam antibiotics on the gastrointestinal microflora (microbiome) of human patients.
Beta-lactam resistance in enterobacteria isolated from animal and water

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