tubulin

(redirected from beta-tubulin)
Also found in: Dictionary, Medical.

tubulin

[′tü·byə·lən]
(biochemistry)
A globular protein containing two subunits; 10-14 molecules are arranged to form a microtubule.
References in periodicals archive ?
Characterization of beta-tubulin genes in hookworms and investigation of resistance-associated mutations using real-time PCR.
Low dose colchicine binding to beta-tubulin results in curved tubulin dimer and prevents it from adopting a straight structure, due to a steric clash between colchicine and beta-tubulin.
Yoo, "Induction of tolerance by oral administration of beta-tubulin in an animal model of autoimmune inner ear disease," ORL, vol.
Assays to detect beta-tubulin codon 200 polymorphism in Trichuris trichiura and Ascaris lumbricoides.
mesentericum using as molecular markers the beta-tubulin gene, the (GTG)5 microsatellite and the M13 minisatellite; 3) to assess phylogenetic relationships among the above mentioned truffles species and try to determine the taxonomic position of T.
Maille et al., "Class III beta-tubulin expression predicts prostate tumor aggressiveness and patient response to docetaxel-based chemotherapy," Cancer Research, vol.
Cancer cells acquire mitotic drug resistance properties through beta I-tubulin mutations and alterations in the expression of beta-tubulin isotypes.
Housekeeping genes, such as [alpha]-TUB ([alpha]-Tubulin), [beta]-actin (Beta actin), 18s rRNA (18s ribosomal RNA), 28s rRNA (28s ribosomal RNA), GAPDH (Glyceraldehyde-3-phosphatedehydrogenase), G6PDH (Glucose-6-phosphate dehydrogenase), [beta]-TUB (Beta-Tubulin), RPL32 (Ribosomal protein L32), EF1-[alpha] (Alpha elongation factor), ELF1-[beta] (beta elongation factor), are usually used as endogenous controls for normalization of qRT-PCR data, but the reference gene expression levels can differ under different environment conditions (Radonic' et al.
Characterisation of a beta-tubulin gene from Melampsora lini and comparison of fungal beta-tubulin genes.
Tubulin molecules occur as dimers containing one alpha-tubulin (1TUB_A) and one beta-tubulin (1TUB_B) molecule.
Is class III beta-tubulin a predictive factor in patients receiving tubulin-binding agents?