As shown in Scheme 2, 1,3-eliminationcyclization of [delta]-lactones 3, 5, 7 yielding a bicyclic compound
9 is also a diastereoselective synthesis.
Quinazoline is a bicyclic compound
having two nitrogen atoms, present in same ring in a 1,3 fashion.
(2000) A stable bicyclic compound
with two Si=Si double bonds.
Safrole is a bicyclic compound
in which a benzene ring is fused to a five-member dioxy ring with allylic side chains.
It is exceedingly labile, and rearranges through Michael attack of the oxygen on the enone to a bicyclic compound
, phaseic acid.
Quinazoline nucleus is an interesting molecule among the most important classes of an aromatic bicyclic compounds
with two nitrogen atoms in their structure.
Different alkyl pyrazines and two classes of bicyclic compounds
, 6,7-dihydro-5(H)-cyclopentapyrazines and pyrrolopyrazines, were found in meat volatiles (Mottram, 1998).
Carvone was observed to be more toxic than bicyclic compounds
such as verbinol and thujone .
Einstein, have synthesized strained bicyclic compounds
1 and 2, which may provide some insight into the effect of ring distortion.
For the synthesis of spiroconnected bicyclic compounds
bearing two pharmacophores, hydantoin and N-alkoxyalkylpiperidine, the Strecker reaction was chosen .