Bifunctional chelating agent | Article about bifunctional chelating agent by The Free Dictionary
bifunctional chelating agent
bifunctional chelating agent[¦bī¦fəŋk·shən·əl ′kē‚lād·iŋ ‚ā·jənt]
A reagent with a molecular structure that contains a strong metal-chelating group and a chemically reactive functional group.
References in periodicals archive
Macrocyclics currently manufactures bifunctional chelating agents
that safely link radioisotopes to biological targeting molecules such as antibodies which are valuable tools for imaging and therapy of diseases such as cancer.
DOTA-based bifunctional chelating agents
have been shown to provide exceptional stability to insure that therapeutic radionuclides do not separate from the monoclonal antibodies that target them to tumors," said William Goeckeler, Ph.