bile acid


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Related to bile acid: bile salt

bile acid

[′bīl ′as·əd]
(biochemistry)
Any of the liver-produced steroid acids, such as taurocholic acid and glycocholic acid, that appear in the bile as sodium salts.
References in periodicals archive ?
Primary and secondary bile acids are synthesized by liver cells and gut bacteria, respectively.
Intrahepatic cholestasis of pregnancy: Relationships between bile acid levels and fetal complication rates.
The reasons of the foetal complications related with ICP is not clearly known, but is considered to relate to an increased flux of bile acids into the foetal circulation.
It is well known that bile acids arise from enzymatic oxidation of cholesterol and that hypercholesterolemia leading to hepatic cholesterol accumulation is one of the key hallmarks in NAFLD and NASH [8, 10].
BASD accounts for about 2% of neonatal cholestasis cases, and early primary bile acid replacement treatment can achieve good results.
Results: Significant increase in biliary content and fecal excretion of bile acids was observed in rats fed for 21 days on cholesterol-supplemented and cholesterol-unsupplemented diets containing 6%, 12%, and 18% water-soluble gummy fibers, but 2.
DISCUSSION: Cerebrotendinous xanthomatosis is an autosomal recessive lipid storage disorder caused by mutations in CYP27A gene, located in 2q33-qter, which codes for hepatic mitochondrial sterol 27-hydroxylase, involved in the normal biosynthesis of bile acids.
Semi-synthetic bile acid fxr and tgr5 agonists: physicochemical properties, pharmacokinetics, and metabolism in the rat.
Hypocholesterolemia of Rhizoma Coptidis alkaloids is related to the bile acid by up-regulated CYP7A1 in hyperlipidemic rats.
Taurine in bile acid conjugation and cholesterol excretion -Taurine is incorporated into one of the most abundant bile acids, chenodeoxychloic acid.
Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut.