bile acid

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Related to bile acid: bile salt

bile acid

[′bīl ′as·əd]

(biochemistry)

Any of the liver-produced steroid acids, such as taurocholic acid and glycocholic acid, that appear in the bile as sodium salts.

References in periodicals archive ?

Primary and secondary bile acids are synthesized by liver cells and gut bacteria, respectively.

Western diet may be blamed for chronic liver inflammation

Intrahepatic cholestasis of pregnancy: Relationships between bile acid levels and fetal complication rates.

Alanine aminotransferase as a predictor of adverse perinatal outcomes in women with intrahepatic cholestasis of pregnancy

The reasons of the foetal complications related with ICP is not clearly known, but is considered to relate to an increased flux of bile acids into the foetal circulation.

Frequency of intrahepatic cholestasis of pregnancy in Punjab Pakistan: A single centre study

It is well known that bile acids arise from enzymatic oxidation of cholesterol and that hypercholesterolemia leading to hepatic cholesterol accumulation is one of the key hallmarks in NAFLD and NASH [8, 10].

Liver Cholesterol Overload Aggravates Obstructive Cholestasis by Inducing Oxidative Stress and Premature Death in Mice

BASD accounts for about 2% of neonatal cholestasis cases, and early primary bile acid replacement treatment can achieve good results.

Novel Mutations in the 3[beta]-hydroxy-∆5-C27-steroid Dehydrogenase Gene (HSD3B7) in a Patient with Neonatal Cholestasis

In each case, 1 [beta]g of each bile acid sulfate was incubated with 10 mL sodium acetate buffer (0.

Tandem mass spectrometric determination of atypical 3[beta]-hydroxy-[[DELTA].sup.5]-bile acids in patients with 3[beta]-hydroxy-[[DELTA].sup.5]-[C.sub.27]-steroid oxidoreductase deficiency: application to diagnosis and monitoring of bile acid therapeutic response

Results: Significant increase in biliary content and fecal excretion of bile acids was observed in rats fed for 21 days on cholesterol-supplemented and cholesterol-unsupplemented diets containing 6%, 12%, and 18% water-soluble gummy fibers, but 2.

Effect of water-soluble gummy fiber, water-insoluble neutral detergent fiber isolated from Syzygium cumini seeds on biliary and fecal bile acids and sterols in rats fed a high cholesterol diet

DISCUSSION: Cerebrotendinous xanthomatosis is an autosomal recessive lipid storage disorder caused by mutations in CYP27A gene, located in 2q33-qter, which codes for hepatic mitochondrial sterol 27-hydroxylase, involved in the normal biosynthesis of bile acids.

Cerebrotendinous Xanthomatosis: presented as neuropsychiatric manifestation

Semi-synthetic bile acid fxr and tgr5 agonists: physicochemical properties, pharmacokinetics, and metabolism in the rat.

Unique probiotic targets cardiovascular disease

Hypocholesterolemia of Rhizoma Coptidis alkaloids is related to the bile acid by up-regulated CYP7A1 in hyperlipidemic rats.

The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma Coptidis

Taurine in bile acid conjugation and cholesterol excretion -Taurine is incorporated into one of the most abundant bile acids, chenodeoxychloic acid.

A Life Saving Discovery In LIVER DISORDERS

Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut.