Percutaneous biliary interventions and complications in malignant bile duct obstruction
. Chin Clin Oncol 2016; 5(5): 68.
Comparison of the efficacy of covered versus uncovered metallic stents in treating inoperable malignant common bile duct obstruction
: A randomized trial.
A 10F, 7cm stent relieved bile duct obstruction
The accumulation of toxic bile acids during bile duct obstruction
contributes to the hepatocellular injury.
Mechanical Large Bile Duct Obstruction
.--Cholestasis is generally present in a centrilobular distribution in acute mechanical bile duct obstruction
Postgate, P Vivianos et al., "The use of a novel endoscopically placed radiofrequency probe for the management of malignant bile duct obstruction
," Gastrointestinal Endoscopy, vol.
Therefore, the same dose of miroestrol, deoxymiroe-strol, and ES (0.5 mg/kg/day for 7 days) were employed in the present study to compare the potential of the phytocompounds to that of ES on the regulation of BSEP and MRP2 expression to assess the risk of bile duct obstruction
and benefit of using these compounds as alternatives to ES in HRT.
Common symptoms can include painless jaundice (yellow skin/eyes, dark urine) related to bile duct obstruction
, significant and unexplained weight loss and abdominal discomfort When eventually diagnosed, most sufferers find they have untreatable terminal cancer.
In conclusion, hydatid disease should be included in the differential diagnosis of bile duct obstruction
, especially in endemic countries.
"In essence, the diagnosis requires exclusion of a wide array of other causes of liver injury, including viral and autoimmune hepatitis, bile duct obstruction
, sepsis, hepatic ischemia, and metabolic disorders," the investigators wrote (Gastroenterology 2011 [doi:10.1053/ j.gastro.2011.07.051]).
MRI scans can be modified to visualize the bile ducts better than CT scans (a procedure referred to as MR cholangiography), and, therefore, are better than CT for identifying the cause and location of bile duct obstruction
Common symptoms include pain in the upper abdomen that typically radiates to the back and is relieved by leaning forward, loss of appetite, significant weight loss and painless jaundice related to bile duct obstruction
. All of these symptoms can have multiple other causes.