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(bĭl'härzī`əsĭs), or

snail fever,

parasitic disease caused by blood flukes, trematode worms of the genus Schistosoma. Three species are human parasites: S. mansoni, S. japonicum, and S. haematobium. The disease is prevalent in Asia, some Pacific islands, Africa, the West Indies, South America, Spain, Puerto Rico, and Cyprus. The larvae of the parasite are harbored by snails, which serve as intermediate hosts, and infect humans who bathe in or otherwise come in contact with infested waters. The larvae enter through the skin, migrate via the blood vessels, and mature in the lungs. From there they travel to the veins of the upper or lower intestine or bladder and reproduce. Some eggs pass out in the feces. Others are carried into the liver, where the body surrounds them with white blood cells, forming hundreds of tiny ball-like granulomas that eventually impair the liver's ability to function. It is believed that the flukes settle in blood vessels that have a particular human immune substance, tumor necrosis factor, that they require in order to reproduce.

The disease is characterized by a skin eruption at the site of entry, fever, diarrhea, and other symptoms, depending on the tissues affected; cirrhosis of the liver is common. The disease can be cured with the drug praziquantel, but reinfection can occur. Although symptoms vary according to the species of infecting fluke, all forms can result in general weakening and eventual death. Control of the disease is difficult, but control of the snail populations that serve as intermediate hosts is effective in reducing the incidence of the disease. Proper sanitation and disposal of human wastes are also important.



a disease of the urinary tract and intestine caused by parasitic worms—trematodes of the family Schistosomatidae. It was originally called bilharzia after the German physician T. Bilharz, who discovered the causative agent in 1851.



any one of several diseases of humans and animals caused by helminths of the family Schistosomatidae of the class Trematoda.

Schistosomiases of humans occur mainly in tropical countries. The causative agents belong to the genus Schistosoma, whose females deposit eggs in the small blood vessels of the urinary bladder and intestine. After entering these organs, the eggs are excreted with urine or feces. Larvae (miracidia) emerge from the eggs after they reach water and are ingested by mollusks, in which they reproduce and develop. The cycle is completed with the emergence of larvae with tails (cercariae) in the water. The cercariae penetrate the human body through the skin and mucous membranes. Individuals become infected after working or swimming in bodies of water contaminated by the urine and feces of persons suffering from schistosomiasis or after drinking water from such bodies of water.

Skin rashes, itching, and sometimes fever occur in the early stage of schistosomiasis. If the genitalia and intestine are affected (bilharziasis), the patient feels a sharp pain upon urination, the urine becomes tinged with blood, and chronic colitis, with mucus and blood appearing in the feces, develops. Schistosomiasis is treated with antimony agents, for example, Anthiomaline (or anthiolimine); it is also treated with Ambilhar (or niridazole). The disease can be prevented by protecting lakes and streams from pollution, by banning swimming in stagnant or slow-flowing water in areas where schistosomiasis is endemic, and by boiling drinking water or filtering it through cloth.



A disease in which humans are parasitized by any of three species of blood flukes: Schistosoma mansoni, S. haematobium, and S. japonicum; adult worms inhabit the blood vessels. Also known as bilharzias; snail fever.


a disease caused by infestation of the body with blood flukes of the genus Schistosoma
References in periodicals archive ?
Bilharzia occurs in tropical regions such as in Africa, the Caribbean, eastern South America, Southeast Asia and in the Middle East.
The Bilharzia Urine CCA strip detects the schistosome CCA (present in all Schistosoma species) in the urine of infected individuals.
This practice led to the spread of infectious liver diseases, especially the hepatitis C virus that, together with Bilharzia, has caused liver cancer cases to rise in number in this country.
Also known as bilharzia or "snail fever", this tropical parasitic disease affects over 200 million people, making it one of the most devastating epidemics in the world, second only to malaria.
In Africa invading hyacinth can also harbor the snails that carry bilharzia (Schistosomiasis) and provide hiding places for crocodiles and snakes, increasing the risk of serious injury or death to water users.
Squamous cell cancer (SCC) of the bladder usually occurs secondary to bilharzia in the Middle East, Southeast Asia and South America, where schistosomiasis is endemic and accounts for 59% to 75% of cases.
Beware of crocodiles and bilharzia when wading after your prize
If you look at the general layout of health problems in developing countries, you have a large amount of persistent childhood respiratory illnesses and diarrhoea, and there are many neglected tropical diseases like hookworm and bilharzia.
Lest one should think of taxonomy as sterile and irrelevant, Fortey presents examples of its practical implications, including research towards the eradication of diseases such as bilharzia, the control of harmful insect pests, and development of more productive agricultural crops.
19) Por ejemplo, Isaac Gonzalez Martinez (1871-1954) casi de inmediato hizo un descubrimiento de importancia global: la primera documentacion de la bilharzia en las Americas.
Screening of indigenous plants for possible use in controlling bilharzia transmitting.
A research team supported by the National Institutes of Health Roadmap and the National Institute of Allergy and Infectious Diseases has identified chemical compounds that hold promise as potential therapies for schistosomiasis--also known as bilharzia or snail fever--a parasitic-worm disease that afflicts more than 207 million people worldwide, primarily in developing nations in tropical areas.