Osteoporosis in patients with primary biliary cirrhosis
. Eur J Gastroenterol Hepatol 2010; 22(12): 1397-401.
Heurgue-Berlot et al., "Factors associated with response to therapy and outcome of patients with primary biliary cirrhosis
with features of autoimmune hepatitis," Clinical Gastroenterology and Hepatology, vol.
Caption: Figure 4: Portal area in the nonlesional liver tissue shows a severely injured bile duct (BD) infiltrated by chronic inflammatory cells and surrounded by ill-defined granulomatous inflammation, typical of the early stage of primary biliary cholangitis (formerly called primary biliary cirrhosis
Genetic polymorphisms of vitamin D receptor and genetic polymorphisms of proteins that are implicated in vitamin D synthesis have been reported to play a role in CLD bone disorders, especially in primary biliary cirrhosis
Oku et al., "Polymyositis associated with autoimmune hepatitis, primary biliary cirrhosis
, and autoimmune thrombocytopenic purpura," Modern Rheumatology, vol.
Invernizzi, "The limitations and hidden gems of the epidemiology of primary biliary cirrhosis
," Journal of Autoimmunity, vol.
Pollak, "Emphysematous cholecystitis resulting in secondary biliary cirrhosis
: a rare complication of endoscopic retrograde cholangiopancreatography," ACG Case Reports Journal, vol.
Studies using broader interpretations of the term report a prevalence of 30-40%, while focal biliary cirrhosis
has been reported as occurring in 20-30% of CF individuals, with multilobular cirrhosis in 5-10% .
Key Words: Primary biliary cirrhosis
, Splenomegaly, Anti-mitochondrial antibodies, Alkaline phosphatase
RITPBC: B-cell depleting therapy (rituximab) as a treatment for fatigue in primary biliary cirrhosis
: study protocol for a randomised controlled trial.
 Other rare causes of cirrhosis are Wilson's disease, Haemochromatosis, primary biliary cirrhosis
, primary sclerosing cholangitis and Alpha-1-antitrypsin deficiency.
Ocaliva was granted accelerated approval for the treatment of primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis
, in combination with ursodeoxycholic acid (UDCA) in adults with an inadequate response to UDCA or as monotherapy in adults unable to tolerate UDCA.