Dr Carl Firth, Chief Executive Officer of ASLAN Pharmaceuticals, said: 'Our study of varlitinib is the largest clinical trial conducted to date on biliary tract
cancer patients in China and we are pleased to see the data we have generated welcomed as an important insight into the treatment of BTC by a prestigious academic group like CSCO.'
Abdominal B-ultrasonography reexamination did not find liver abnormality, biliary tract
dilatation and jaundice in those patients.
The five-year survival rate for biliary tract
cancer is approximately 20%, which makes it an intractable cancer with the second worst prognosis following pancreatic cancer.(2) Chemotherapy options are limited in comparison with other cancers, and as such it is a disease with significant unmet medical needs.
Abdominal computed tomography revealed a distended, wide, double-border gallbladder with intracystic extravasation, whereas the biliary tract
appeared normal (Figure 1).
Six rare biliary tract
anatomic variations: implications for liver surgery.
000001, the summary random effects were significant in 35 meta-analyses 31 of these found increased risk with adiposity of esophageal adenocarcinoma, multiple myeloma, and cancers of the colon, rectum, liver, biliary tract
system (cancers of gallbladder, extrahepatic bile duct, and ampulla of Vater), pancreas, postmenopausal breast, endometrium, and kidney.
The lowest rates of skin eruption were in patients with gallbladder and biliary tract
, colon, pancreas, and liver malignancies.
According to the World Health Organisation, prolonged use of Ketamine can cause adverse physical effects, particularly urinary and biliary tract
Variations of the biliary tract
were categorized into seven groups according to the classification of McSweeney et al.
It may help surgeons to confirm the biliary anatomy before dividing any ductal structures, and thus prevent BDI, or to confirm BDI intraoperatively., However, routine use of IOC is still under debate., Many techniques have been developed for biliary tract
evaluation, such as laparoscopic ultrasonography, dye cholangiography, and near-infrared fluorescence cholangiography. Many comparative studies are still ongoing to determine whether these techniques are superior in regard to safety, accessibility, ease of interpretation, and radiation exposure.
Hemobilia, in the most elemental sense, refers to the admixture of blood in bile or to blood in the biliary tract
. The most common causes of hemobilia are surgical and nonsurgical trauma, malignancy, and/or cholangiovenous (or arterobiliary) fistulae.
Therefore, the structure of the bifurcation, especially the anatomy of the biliary tract
, should be assessed very well before the operation, and possible ultrasonography, computed tomography, magnetic resonance cholangiopancreatography (MRCP), and endoscopic imaging methods should be used carefully [3, 4].