For each arm, the number of patients who had myocardial infarction out of a total [n.sub.t] is considered to be the number of successes in [n.sub.t] binomial trials
. Similarly, the number of cases in the control group is treated as a binomial outcome independent of the treatment group.
The beta-binomial distribution is used to model the number of successes in n binomial trials
when the probability of success is p with a beta distribution with parameters a and b.
(Transaction costs-or the bookie's "vigorish"-make the bettor's breakeven rate 52.4 percent.) Twenty-three of those rules were nonrandom at the p < 0.05 level where winning and losing bets constitute binomial trials
and the probability of x wins is found by: