biomarkers


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biomarkers

[′bī·ō‚mär·kərz]
(geology)
Complex organic compounds found in oil, bitumen, rocks, and sediments that are linked with and distinctive of a particular source (such as algae, bacteria, or vascular plants); they are useful dating indicators in stratigraphy and molecular paleontology. Also known as chemical fossils; molecular fossils.
References in periodicals archive ?
The global cancer biomarkers market is projected to reach USD 20.
Biomarkers Congress 2017, in the hands of clinical investigators, provide a dynamic and powerful approach to understanding the spectrum of diseases with obvious applications in analytic epidemiology, biomarkers and clinical research in disease prevention, diagnosis, and disease management.
Utilizing public data from the development of multiple ALK inhibitors and the performance characteristics of multiple diagnostic tests for disease relevant biomarkers, Richard Buller will discuss how opportunities for the advancement of regulatory science have evolved and come to fruition in both the drug and diagnostic spaces.
Specialists in neurological and neuropsychological disorders and in the role of biomarker research in these disorders look at biomarker technology generally and at specific biomarkers for injury and other disorders of the central nervous system.
One of the best ways to diagnose cancer early, aid in its prognosis, or predict therapeutic response, is to use serum or tissue biomarkers.
Currently the most important applications of biomarkers are in drug discovery and development.
PBI's biomarkers include therapeutics areas of cardiovascular diseases, diabetes, obesity, acute kidney injury, musculoskeletal disorders, and inflammation.
In a study that evaluated 3 biomarkers suggested to indicate plaque rupture [myeloperoxidase (MPO), matrix metalloproteinase 9 (MMP-9), and pregnancy-associated plasma protein A (PAPP-A)] for the early diagnosis of AMI, the diagnostic information was almost nil.
The chapter on technology covers many different platforms for detecting biomarkers.
Before we incorporate their conclusions into our clinical practice, we have to be aware of the limitations of these non-specific biomarkers.
Louis, has initiated a collaboration with leading researchers at University of Glasgow to discover novel epigenetic biomarkers for the development of tests that screen for cancer at an early stage and provide personalized information about how tumors are most effectively treated.
Key words: biomarkers, chemical exposure, epidemiology, gene-environment interactions, genomics, occupational cancer, polymorphisms, proteomics, risk assessment, toxicogenomics.