biotin


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biotin:

see vitaminvitamin,
group of organic substances that are required in the diet of humans and animals for normal growth, maintenance of life, and normal reproduction. Vitamins act as catalysts; very often either the vitamins themselves are coenzymes, or they form integral parts of coenzymes.
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; coenzymecoenzyme
, any one of a group of relatively small organic molecules required for the catalytic function of certain enzymes. A coenzyme may either be attached by covalent bonds to a particular enzyme or exist freely in solution, but in either case it participates intimately in
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.

Biotin

A vitamin, widespread in nature. It is only sparingly soluble in water; it is stable in boiling water solutions, but can be destroyed by oxidizing agents, acids, and alkalies. Under some conditions, it can be destroyed by oxidation in the presence of rancid fats. Biotin's occurrence in nature is so widespread that it is difficult to prepare a natural deficient diet. Biotin deficiency in animals is associated with dermatitis, loss of hair, muscle incoordination and paralysis, and reproductive disturbances. Biotin deficiency produced in humans by feeding large amounts of egg white resulted in dermatitis, nausea, depression, muscle pains, anemia, and a large increase in serum cholesterol. See Coenzyme

Biotin

 

(vitamin H), a water-soluble vitamin contained in yeasts and other microorganisms, and also in liver, egg yolk, kidneys, milk, cauliflower, and other vegetable products. The daily requirement of humans for biotin (0.25 mg) is usually provided by the microflora of the intestinal tract; it is therefore unnecessary to introduce it in the diet. Biotin has been obtained synthetically.

Avitaminosis H may be produced in laboratory animals by feeding large quantities of raw egg white, which contains a biotin antagonist, avidin, which decomposes when heated to 100° C. Affection of the skin of the seborrheic type is observed in avitaminosis H. Biotin is a coenzyme and participates in the transfer of carbon dioxide gas and its fixation in biosynthesis; its other functions have not been clarified.

biotin

[′bī·ə·tən]
(biochemistry)
C10H16N2O3S A colorless, crystalline vitamin of the vitamin B complex occurring widely in nature, mainly in bound form.

biotin

a vitamin of the B complex, abundant in egg yolk and liver, deficiency of which causes dermatitis and loss of hair. Formula: C10H16N2O3S
References in periodicals archive ?
The global Biotin Market is expected to witness rapid growth in the near future due to the increasing demand for biotin products by end-user industries across the globe.
High serum levels of biotin can make the assays inaccurate, with lower-than-actual TSH and higher-than-actual thyroid hormone levels.
Despite its uncertain efficacy, biotin is safe and relatively inexpensive, so a clinical trial in selected patients with multiple sclerosis seems reasonable.
The patient disclosed that she had been taking a biotin supplement, and after comprehensive workup, including a scheduled surgical procedure, abnormalities were attributed to biotin interference.
When I heard about this safety alert, I checked my vegan multi-vitamin and learned that it contains 100 micrograms of biotin. I'll be looking for a new supplement.
To functionalize the SPR sensor with biotin, Aucoated glass slide was first cleaned ultrasonically with 4% sodium dodecyl sulfate (SDS) solution and rinsed with deionized water.
Four reference oligonucleotides were utilized as target sequences: oligonucleotides B-d[A.sub.20] and B-d[C.sub.20] were designed to contain a biotin molecule in their 5' end, in order to interact with Au NPs functionalized with anti-biotin antibody.
* Biotin and silicon have been documented to enhance these rejuvenation effects.
Conversely, at biotin concentrations of 1.0, 2.5, 5.0, 15 g/ ml, significantly less improvement in glu production was noticed, but at 10 g/ml a nearly 2.2-fold increase in QP was observed, though the only statistically significant difference was in the QS value.
Falsely low parathyroid hormone secondary to biotin interference: a case series.
Biotin, an essential B vitamin, fortifies them against further damage.
The physiological role of the vitamin biotin (also named B7) is to participate as a coenzyme of carboxylases [1].