biotransformation


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biotransformation

[¦bī·ō‚tranz·fər′mā·shən]
(biochemistry)
The series of chemical reactions that occur in a compound, especially a drug, as a result of enzymatic or metabolic activities by a living organism.
References in periodicals archive ?
Biotransformation appeared to be the dominant elimination process of PFPiAs in rats, which corroborates the low proportion of PFPiAs found in urine and feces of rats dosed with the commercial mixture (D'eon and Mabury 2010).
Some SNPs affect the liver's biotransformation pathways in humans.
Drug biotransformation via this system of enzyme is one of the major routes through which potential DIs take place leading to drug toxicities, ADRs, or therapeutic failure.
Aldehyde dehydrogenase 2 is a key enzyme mediating the biotransformation of NTG, [sup][12] which consequently mediates the biological activation of NTG.
Microarray analysis revealed a significant regulation of genes and signal cascades related to biotransformation.
This fermentation involved two phases, first phase to attain the suitable level of cell density while second phase is the biotransformation phase.
In addition to the multiple reaction sequences of fermentations, fungi are extremely useful in carrying out biotransformation processes.
Biotransformation involves natural processes to transform raw materials into ingredients to improve the flavour, digestibility or shelf life of food.
The biotransformation of (+)-limonene using different microorganisms (i.