Histomoniasis or blackhead disease is a life-threatening disease of turkeys that is caused by a flagellated protozoan, Histomonas meleagridis.
Histomonas meleagridis, blackhead disease, nitarsone, metronidazole, turkeys.
This form of transmission occurs when sick turkeys huddle together and allows for rapid spread of blackhead disease in the absence of H.
Historically, blackhead disease could be readily treated or prevented by the use of nitroimidazole drugs (Lucas, 1962; van der Heijden and Landman, 2007; Reynolds et al., 2009).
There is no approved vaccine or treatment for blackhead disease, although an organoarsenic compound, nitarsone (4-nitrophenylarsonic acid), may be used for prevention (McDougald, 2005; Grabensteiner et al., 2007; Abraham et al., 2014).
meleagridis and should be considered when designing experiments and testing compounds to inhibit blackhead disease. In addition, our studies show high efficacy of nitarsone than metronidazole against field isolate of H.
Blackhead Disease: Reduced sensitivity of Histomonas meleagridis to nitarsone in vitro and in vivo Avian Dis., 58: 60-63.
Blackhead disease (histomoniasis) in poultry: a critical review.