We also evaluated the peripheral blood blast cell
percentage as well as bone marrow blast cell
Recent study shows that ANFIS has been used for the classification of blast cell
in leukaemia patients by microscopic blood image analysis, where it gives appropriate results .
PML/RAR[alpha] complexes can bind to the predicted PML/RAR[alpha] binding site in the promoter region of miR-146a, and the repressive effects of PML/RAR[alpha] complexes can be blocked by ATRA, even in primary blast cells
The blast counts on the first presentation of ALL patients showed that majority of ALL cases, 21 cases (56.76%) showed blast cells
between 50 to 80% followed by 8 cases (21.63%) showed more than 80% blast cells
Clinical and laboratory characteristics at diagnosis were statistically correlated (age, sex, WBC count, hemoglobin level, PLT count, blast cells
rate) with t(5;17), t(8;21), inv(16) chromosomal aberrations, and FLT3 mutations (Table 1).
In this study, univariate analysis showed that T-ALL, high LDH at diagnosis, age ≥35 years, blast cell
proportion ≥5% on the 15 [sup]th day of induction therapy, and extramedullary infiltration before HSCT were the poor prognosis factors.
To support the new freezer and blast cell
operations, the low temperature distribution and food processing facility has an upgraded machine and mechanical room.
It is based on number of blast cells
and partially or fully differentiated mature cell type on smear of the blood and/or bone marrow sample.
60% of the patients having blast cell
less than 20% and 66.66% having blast cell
more than 20% have no retinopathy.
As a matter of fact, in a more recent study (140) on a series of 111 AML patients in which multivariate information provided by the use of multiple stainings analyzed at flow cytometry was obtained, it has been shown that the combination of three phenotypic variables (the number of major blast cell
populations, the pattern of CD34/CD15 expression, and the reactivity for CD13) was highly sensitive (100%) and specific (99%)for the selection of AML cases carrying PML/RAR-[alpha] gene rearrangements as demonstrated by the combined use of the reverse transcription-PCR and fluorescence in situ hybridization.
The blast cell
suspensions were thawed at room temperature.
Combined evaluation of the Blast flag with the Abn Lympho/L_Blasts flag on the XE-2100 did not increase the sensitivity of blast cell
flagging but resulted in an increase of FP results.