The
bleeding time test has largely been replaced with automated platelet function assays as a screening test to evaluate platelet function because of the poor reproducibility and wide variability of
bleeding time tests.
The Compound I showed proagregate activity upon intraperitoneal injection to laboratory rats, being more effective than etamsylate, reducing the amount of blood loss and
bleeding time.
Relevant data like age, sex, occupation, details of the cardiovascular illness including details of CCB therapy, spontaneous bleeding manifestations if any, the results of complete blood count,
bleeding time, clotting time and prothrombin time and Hess test were recorded in a proforma.
The diagnosis of vWD is on the basis of deranged activated partial thromboplastin time (aPTT), prolonged
bleeding time (BT) and decreased factor VIII activity in presence of normal prothrombin time (PT) and normal platelet count but impaired platelet function defects.
13) Although
bleeding time may be prolonged in patients that take antiplatelet agents, it may not be clinically relevant when determining the risk versus benefit of continued treatment with dental procedures.
We compared the
bleeding time in early and late follicular phases because estrogen levels are relatively very low and very high9 during these phases respectively.
27) Treatment with either the combination of rFVIIa plus a 4-factor PCC or treatment with factor eight inhibitor bypass activity (FEIBA, an activated PCC) improved the
bleeding time but had an insignificant effect on blood loss.
He aptly described the abnormalities as, abnormally prolonged
bleeding time, with normal platelet count, and poor aggregation of platelets and peripheral smear showing platelets seen in singly.
Bleeding time was also determined before induction of hypotension and at 30 and 60 minutes, by puncture of the inner side of the ear using a lancet after antiseptic skin preparation.
A 9-year old female patient was referred to our center with a diagnosis of von-Willebrand factor deficiency when her
bleeding time was found to be prolonged (10 minutes) in an external center where she was being followed up because of extensive eccyhmoses and epistaxis which had been lasting since the age of four years.
Anti-clotting agents such as warfarin and heparin reduce risk of heart and brain clots but increase the
bleeding time .
The safety of these drugs when used concomitantly is not proven especially on prolongation of
bleeding time, and the risk of hemorrhage.
