blood substitute


Also found in: Dictionary, Thesaurus, Medical, Legal, Financial, Wikipedia.

blood substitute,

substance that mimics the function of blood. Blood substitutes typically concentrate only on reproducing the function of hemoglobinhemoglobin
, respiratory protein found in the red blood cells (erythrocytes) of all vertebrates and some invertebrates. A hemoglobin molecule is composed of a protein group, known as globin, and four heme groups, each associated with an iron atom.
..... Click the link for more information.
, the molecule that carries oxygen through the body, and do not attempt to replicate the blood's other functions. Blood donated by humans must be refrigerated, can be contaminated by such diseases as AIDSAIDS
or acquired immunodeficiency syndrome,
fatal disease caused by a rapidly mutating retrovirus that attacks the immune system and leaves the victim vulnerable to infections, malignancies, and neurological disorders. It was first recognized as a disease in 1981.
..... Click the link for more information.
 and hepatitishepatitis
, inflammation of the liver. There are many types of hepatitis. Causes include viruses, toxic chemicals, alcohol consumption, parasites and bacteria, and certain drugs.
..... Click the link for more information.
, and is often in short supply. Designers of blood substitutes hope to eliminate these problems and develop genetically engineered or chemical products that will be tolerated by people of all blood types. Some blood substitutes under development use hemoglobin derived from human blood that is too old for use in blood transfusions.
References in periodicals archive ?
The blood substitute can prove to be a boon for many patients who face the problem of unavailability of blood in emergency situations.
A team of researchers at Delhi University's department of Biochemistry, led by professor Suman Kundu, has applied for a patent for laboratory-made haemoglobin which, according to them, enjoys several advantages as a blood substitute.
Washington, Dec 05 ( ANI ): A research team has found a way to stabilize hemoglobin, the oxygen carrier protein in the blood, a discovery that could lead to the development of stable vaccines and affordable artificial blood substitutes.
Setbacks in blood substitutes research and development: a biochemical perspective.
Vampire scientist Edward (Ethan Hawke), is struggling to create a stable, synthetic blood substitute when he meets a human survivor, who introduces him to resistance leader Elvis (Willem Dafoe).
Humans are harvested in what can best be described as 'farms' while top scientists try to find a blood substitute to help solve the famine.
Humans account for 5% of the population and are captured by the vampires to be drained of their blood, but this precious resource has almost run dry and the dominant species face possible extinction unless it can engineer a blood substitute.
It's set in a tiny Louisana town in a time when vampires are living alongside humans, thanks to a synthetic blood substitute called Tru Blood.
For one thing, he's a vegan who uses a soy blood substitute. He was "turned" by accident, and he's a gawky geek, not beautiful like the other vampires.
(6) Allowing first responders to administer blood substitute to unconscious patients when blood loss is critical and there is no legal representative to consent for the patient meets these criteria.
For years, hematologists have longed for a suitable blood substitute, also known as a "synthetic oxygen carrier." An ideal blood substitute would eradicate the risk of disease transmission, most notably HIV and hepatitis; be compatible with all blood types; have a shelf life approximately four times that of donated human blood; and prove hugely beneficial in cases of trauma--at home or on the battlefield--as well as for transfusions during surgery.
He had lost a lot of blood and his blood pressure was so low that we had no choice but to inject a blood substitute straight into his bone marrow.