Borrelia


Also found in: Dictionary, Thesaurus, Medical, Wikipedia.

Borrelia

A genus of spirochetes that have a unique genome composed of a linear chromosome and numerous linear and circular plasmids. Borreliae are motile, helical organisms with 4–30 uneven, irregular coils, and are 5–25 micrometers long and 0.2–0.5 μm wide. All borreliae are arthropod-borne. Of the 24 recognized species, 21 cause relapsing fever and similar diseases in human and rodent hosts; two are responsible for infections in ruminants and horses; and the remaining one, for borreliosis in birds. See Bacteria

The borreliae of human relapsing fevers are transmitted by the body louse or by a large variety of soft-shelled ticks of the genus Ornithodoros. The species B. burgdorferi, the etiologic agent of Lyme disease and related disorders, is transmitted by ticks of the genus Ixodes. Borrelia anserina, which causes spirochetosis in chickens and other birds, is propagated by ticks of the genus Argas. Various species of ixodid ticks are responsible for transmitting B. theileri among cattle, horses, and sheep. Borrelia coriaceae, isolated from O. coriaceus, is the putative cause of epizootic bovine abortion in the western United States.

Polyacrylamide gel electrophoresis of spirochetes has shown that the outer surface of the microorganisms contains numerous variable lipoproteins of which at least two are abundant. The antigenic variability is well known for the relapsing fever borreliae. A switch in the major outer-surface proteins leads to recurrent spirochetemias. Tetracyclines, penicillins, and doxycycline are the most effective antibiotics for treatment of spirochetes. Two vaccines consisting of recombinant B. burgdorferi have been evaluated in subjects of risk for Lyme disease. Both proved safe and effective in the prevention of this disease. See Antibiotic, Medical bacteriology

Borrelia

[bə′rel·ē·ə]
(microbiology)
A genus of bacteria in the family Spirochaetaceae; helical cells with uneven coils and parallel fibrils coiled around the cell body for locomotion; many species cause relapsing fever in humans.
References in periodicals archive ?
Se establecio la presencia de anticuerpos sericos IgG especificos anti-Borrelia burgdorferi por la tecnica de ELISA (Ridascreen[R] Borrelia IgG.
Acknowledgments: We thank the Department of Biotechnology for collaboration in the development of fluorescent lanthanide labels, and for providing the Borrelia cells.
The TBRF ImmunoBlot is designed to detect antibodies to specific antigens of TBRF Borrelia in human serum.
Lyme hastaligi, Borrelia burgdorferi isimli Spiroket in neden oldugu, deri, eklemler, kalp ve santral sinir sistemi gibi cok sayida sistemi tutan bir zoonozdur.
Chromosome and linear plasmid sequences of a 2015 human isolate of the tick-borne relapsing fever spirochete, Borrelia turicatae.
The occurrence of negative results in WB from some of the samples that gave positive results in the ELISA may be due to cross reaction of Lyme borrelia with other pathogens.
Borrelia afzelii causes a distinct skin infection known as acrodermatitis chronica atrophicans (ACA), and B.
Using the LM-method, 14 (66%) patient group blood samples and 35 (85%) control group samples were judged positive for Borrelia and/or Babesia.
The newly discovered bacteria, provisionally named Borrelia mayonii, caused Lyme disease with symptoms similar to those caused by B.
Polymerase chain reaction real time (RT-PCR) assay for Borrelia burgdorferi sensu lato detection, performed on DNA obtained from peripheral blood, was positive.
Key words: Borrelia anserina, Argas persicus, poultry industry.
Borrelia burgdorferi was first described as a gram-negative treponema-like organism with irregular coils, 10 to 30 mm in length and 0.