osteogenesis imperfecta

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osteogenesis imperfecta

[¦äs·tē·ō′jen·ə·səs ‚im·pər′fek·tə]
(medicine)
A disease inherited as an autosomal dominant and characterized by hypoplasia of osteoid tissue and collagen, resulting in bone fractures.
References in periodicals archive ?
As part of a worldwide study to gauge raloxifene's effects on osteoporosis, scientists gave the drug to two-thirds of a group of 7,705 postmenopausal women with the brittle-bone disease.
A recently approved blood test can rapidly assess changes in bone density in people with the brittle-bone disease osteoporosis, according to experts who spoke here last week at the annual meeting of the American College of Rheumatology.
Elderly women with vision impairment and poor motor skills are at increased risk for sustaining a hip fracture from a fall, regardless of whether they have the brittle-bone disease osteoporosis, according to a new study of French women.
Low calcium intake, it says, is leading to an increase in cases of osteoporosis, or brittle-bone disease.