bronchodilation


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bronchodilation

[¦bräŋ·kō‚dī′lā·shən]
(physiology)
Widening of the air passages in bronchi and bronchioles.
References in periodicals archive ?
Absence of bronchodilation during desflurane anesthesia: a comparison to sevoflurane and thiopental.
PGE receptors have been shown to mediate many physiological events, such as pain, fever, platelet aggregation, gastric cytoprotection, bone health, airway protection, ovulation, fertilization, bronchodilation, vasodilatation, angiogenesis, cytokine, and chemokine modulation.
Mitigation of vagal stimulation rebalances autonomic system and is claimed to be responsible for bronchodilation and thereby reducing RAW.
While bronchodilation is recognised as the foundation of COPD therapy, many patients may continue to struggle with symptoms and exacerbations over time.
A recent research - CLAIM Study - is the first to investigate the effects of dual bronchodilation on cardiac function and lung hyperinflation.
Early pharmacogenetic studies in two cohorts of asthmatic children demonstrated that Arg16 homozygotes experience greater forced expiratory volume during the first second (FEV1) bronchodilation in response to one-time administration of albuterol compared with Gly16 homozygotes.14-16
Aclidinium (Figure 1(a)) acts through its binding to M3 receptors located on the bronchial smooth muscle and the vascular endothelium in the lung thus resulting in bronchodilation [2, 3].
Further potential mechanisms that may increase pulmonary retention time include slow receptor off-kinetics [26, 63, 64], esterification in the lung tissue [65], and interaction with membrane lipid bilayers, the latter of which is proposed to account for the long duration of bronchodilation provided by the LABAs salmeterol and formoterol [66].
Devolder et al., "Computational fluid dynamics can detect changes in airway resistance in asthmatics after acute bronchodilation," Journal of Biomechanics, vol.
Apart from bronchodilation [10-12], our coworkers have confirmed that sevoflurane suppressed allergic airway inflammation by inhibiting inflammatory infiltrates and mucus production, as well as keeping balance of cytokine responses [13].
The trial also met its primary bronchodilation endpoint, demonstrating non-inferiority to tiotropium bromide once-daily.
The rationale for this change is that LABA/LAMAs give greater bronchodilation compared with LABA/ICS, and one study showed a decreased rate of exacerbations compared to LABA/ICS in patients with a history of exacerbations.