Brush Border

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brush border

[′brəsh ‚bȯr·dər]
(cell and molecular biology)
A superficial protoplasic modification in the form of filiform processes or microvilli; present on certain absorptive cells in the intestinal epithelium and the proximal convolutions of nephrons.

Brush Border


the aggregate of rod-shaped structures on the surface of certain cells in animals and humans. The brush border consists of separate cytoplasmic processes arranged like a brush along the free margin of the cells of the excretory ducts of the salivary glands, the convoluted uriniferous tubules of the kidney, and certain other epithelial cells. By substantially increasing the cell surface, the brush border promotes more intensive absorption and excretion of matter.

References in periodicals archive ?
Caption: Figure 1: Hypothetical model depicting the mechanism by which a brush border enzyme intestinal alkaline phosphatase (IAP) affects the intestinal microbiota, the release of bacterial LPS-induced inflammation, and the luminal content of ATP inhibiting the commensal bacteria of different origin.
Early Work on Small Intestinal Organ Culture and the Study of Brush Border Enzymes in CD.
At the same time, the levels of brush border enzymes decrease and accumulate in the medium.
Several authors investigated the proteins, the DNA content, and the brush border enzymes in small intestinal biopsy OC.
In addition, Caco2 cells express considerably lower amounts of brush border enzymes in comparison to normal enterocytes [44].