Zhang et al., "Clinical features and factors associated with severity and fatality among patients with severe fever with thrombocytopenia syndrome bunyavirus
infection in Northeast China," PLOS ONE, vol.
A family cluster of infections by a newly recognized bunyavirus
in Eastern China, 2007: further evidence of person-to-person transmission.
Bunyaviruses cause diseases that include Rift Valley fever (a virus found in Africa that is transmitted to humans and livestock by mosquitoes) and Crimean-Congo hemorrhagic fever (a bunyavirus
found in Africa, Asia, and Europe that is carried by ticks and causes a highly pathogenic hemorrhagic fever).
Most arboviruses of public health importance belong to one of three virus genera: Flavivirus, Alphavirus, and Bunyavirus
. Human cases caused by the following domestic arboviruses are nationally reportable to CDC: West Nile, St.
that typically causes severe encephalitis and neurologic sequelae in children younger than 16 years of age 32.
La Crosse virus (LACV), a California serogroup bunyavirus
, is a leading cause of pediatric arboviral encephalitis in the United States and is transmitted primarily by the eastern treehole mosquito (Aedes triseriatus) (1).
La Crosse bunyavirus
nonstructural protein NSs serves to suppress the type I interferon system of mammalian hosts.
La Crosse encephalitis virus (LACV) is a mosquitoborne bunyavirus
of the California encephalitis serogroup (1).