calciphylaxis


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calciphylaxis

[‚kal·sə·fə′lak·səs]
(immunology)
A sudden local calcification in tissues in response to induced hypersensitivity following systemic sensitization by a calcifying factor.
References in periodicals archive ?
Successful treatment of calciphylaxis with clnacalcet- an alternative to parathyroidectomy?
A case study, calciphylaxis: An exercise in human caring.
Calciphylaxis. Chicago: University of Chicago Press; 1962.
Some case studies indicate that bisphosphonates such as etidronate [210] and pamidronate 208] are useful in treating calciphylaxis (uremic arteriolopathy) in patients with high bone turnover [208], which is a life-threatening complication of CKD.
Tumour calcification complicated with calciphylaxis is rare in end-stage renal disease and is associated with high mortality.
An example of this is calciphylaxis pain, which can be extremely difficult to manage and sudden escalations can occur without warning.
Soft-tissue calcifications may be classified into metastatic (abnormal serum calcium-phosphorus levels), tumoral (elevated phosphorus but normal calcium levels), dystrophic including calcinosis (normal serum calcium-phosphorus levels but damaged tissue), idiopathic (no abnormalities detected) and calciphylaxis (chronic renal failure with abnormal calcium-phosphorus levels).(4) Calcifications occurring in the skin and subcutaneous tissue of patients with SLE are dystrophic/ calcinotic in nature.
The first clinical differential diagnoses were cutaneous SLE, nephrogenous dermatopathy, calciphylaxis, and calcinosis.