Antitumor agent calixarene
0118 targets human galectin-1 as an allosteric inhibitor of carbohydrate binding.
Derivatives of calix[n]arenes could be formed by inserting binding groups such as amines and/or alcohols into the upper and lower rim positions of the calixarene
Bao, "Induced sensitivity and selectivity in thin-film transistor sensors via calixarene
layers," Advanced Materials, vol.
Ertul, "Fabrication of calixarene
based protein scaffold by electrospin coating for tissue engineering," Journal of Nanoscience and Nanotechnology, vol.
, Metal cations, Copolymer, Chromium(VI), Toxicity, Thioether.
OTX008 was lately reported as a novel calixarene
compound which is derived from anginex and bonded to Gal-1 on the side back face, far away from the [beta]-galactoside binding site [16-18].
is a typical representative of the third-generation host molecule following crown ether and cyclodextrin.
Although specific literature has often reported the use of additives, such as albumin and polyethylene glycol (SOARES et al., 2003), sporopollenin (YILMAZ et al., 2010), zeolite (VIDINHA et al., 2006), calixarene
derivatives (SAHIN et al., 2009), ionic liquid (SOUZA et al., 2013), the use of ionic liquids (IL) in all areas of chemical industries has an excellent prospective due to their unique properties (KESKIN et al., 2007).
They cover highly selective extractants and a better understanding of phase-transfer phenomena, supramolecular interactions in the outer coordination spheres of extracted metal ions, molecular design and metal extraction behavior of calixarene
compounds as host extractants, protein extraction by the recognition of lysine residues using macrocyclic molecules, interfacial molecular aggregation in solvent extraction systems, and supramolecular aspects of stable water-in-oil microemulsions in chemical separations.
and calixresorcarene glycosides: their synthesis and biological applications," Chemical Reviews, vol.
Skiba, "Method for synthesizing calixarene
and/or cyclodextrin copolymers, terpolymers and tetrapolymers, and uses thereof," Patent PCT/FR2010/000876, 2010.