calmodulin

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calmodulin

[kal′mäj·ə·lən]

(biochemistry)

A calcium-modulated protein consisting of a single polypeptide with 148 amino acids and a molecular weight of 16,700, found in all eukaryotes.

References in periodicals archive ?

Further studies are necessary to determine whether other Ca 2+ signaling molecules, such as protein kinase C, calmodulin kinases, and cytoskeletal proteins, also participate in the MFN2-mediated immune function of T cells.

Role of the Ca2+-Calcineurin-Nuclear Factor of Activated T cell Pathway in Mitofusin-2-Mediated Immune Function of Jurkat Cells

In our experiment, 4 myo-inositol-1-phosphate synthase genes and 3 calmodulin genes participated in the resistance to low temperature stress, and the expression of calmodulin genes continued to increase during low temperature treatment.

Identifying Differentially Expressed Genes Associated with Tolerance against Low Temperature Stress in Brassica napus through Transcriptome Analysis

It may transduce the signal to downstream transcription factors including Calmodulin Binding Transcription Activators (CAMTAs) (Pandey et al.

PLANTS SENSORY-RESPONSE MECHANISMS FOR SALINITY AND HEAT STRESS

The highest homology of CaLc was found in bovine brain calmodulin.

Calcium inhibition as an intracellular signal for actin-myosin interaction

The relationship between calmodulin binding and phosphorylation of smooth muscle myosin kinase by the catalytic subunit of 3':5' cAMP-dependent protein kinase.

Endothelium-independent vasorelaxant effect of a Berberis orthobotrys root extract via inhibition of phosphodiesterases in the porcine coronary artery

Inhibition of cell proliferation and glyoxalase-I activity by calmodulin inhibitors and lithium in Brassica oleracea.

Methylglyoxal and glyoxalase system in plants: old players, new concepts

Weiss, "Oxidative stress-induced afterdepolarizations and calmodulin kinase II signaling," Circulation Research, vol.

Cellular and molecular mechanisms of arrhythmia by oxidative stress

The benzothiazoles also have immuno-suppressive, antiviral [18,19], and calmodulin (CaM) antagonists [20] activities.

Antileishmanial Activities of Benzothiazole Derivatives

This model also predicts that changes in the calcium amplitude will strongly determine the activation of calmodulin, with a 5-fold increase in calcium amplitude causing an almost 1000-fold increase in active calmodulin (Gamble and Koch, 1987).

Calcium: amplitude, duration, or location?

PMCAs are regulated by calmodulin, a calcium-activated protein with multiple targets, as well as other mechanisms giving stringent local control to the activation of the PMCA.

The aging brain part 2: calcium homeostasis and a theory of brain aging

8] Human genes: PPIA, peptidylprolyl isomerase A (cyclophilin A); PPP3R1, protein phosphatase 3, regulatory subunit B, a; PPP3CA, protein phosphatase 3, catalytic subunit, a isozyme; PPP3CB, protein phosphatase 3, catalytic subunit, isozyme; FKBP1A, FK506 binding protein 1A, 12 kDa; CALM1, calmodulin 1 (phosphorylase kinase, 8); IL2, interleukin-2; IL2RA, interleukin 2 receptor, a; JUN, jun proto-oncogene; NFATC1, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1.

Tacrolimus pharmacodynamics and pharmacogenetics along the calcineurin pathway in human lymphocytes

The precise control of this movement relies on the direct physical interaction between a calcium channel protein ryanodine receptor (RYR), and a calcium-sensing protein called calmodulin.