Cachexia

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Related to Cancer cachexia: paraneoplastic syndrome

cachexia

[ka′kek·sē·ə]
(medicine)
Weight loss, weakness, and wasting of the body encountered in certain diseases or in terminal illnesses.

Cachexia

 

a state of profound wasting and physical debility manifested by severe emaciation, weight loss, dry and flabby skin, loss of hair, disappearance of subcutaneous fat, atrophy of muscles and viscera, and low serum protein level. Edema, hemorrhages, and sometimes mental derangement can occur with cachexia. It results from prolonged malnutrition or starvation, severe metabolic disorders, chronic arsenic, lead, mercury, or fluorine poisoning, and severe lesions of the digestive tract (atrophy of the intestinal mucosa, condition after resection of the stomach and intestines). Cachexia may occur in severe cases of tuberculosis or other chronic infections, some lesions of the endocrine glands, (hypophysis, thyroid, adrenals, pancreas), large slow-healing wounds, abscesses, and malignant tumors (especially of the esophagus and stomach).

References in periodicals archive ?
Their studies demonstrated that TNF[alpha] is linked with increased lipolysis, and zinc-[[alpha].sub.2]-glycoprotein (ZAG), which has been identified as a novel adipokine, is upregulated in cancer cachexia which promotes lipid breakdown and can potentially serve as a novel target for preventing adipose atrophy in malignant conditions.
IL-6 is a pleiotropic cytokine implicated as a critical regulator of inflammation-induced skeletal muscle and fat wasting during cancer cachexia [35].
Anker et al., "Definition and classification of cancer cachexia: an international consensus," The Lancet Oncology, vol.
Results of a pilot study of the effects of celecoxib on cancer cachexia in patients with cancer of the head, neck, and gastrointestinal tract.
* Identify and understand important and diverse types of therapeutics under development for Cancer Cachexia.
The role of glucocorticoids in the induction of zinc-alpha2-glycoprotein expression in adipose tissue in cancer cachexia. Br J Cancer 2005;92:876-81.
An energy and protein dense, high n-3 fatty acid oral supplement promotes weight gain in cancer cachexia. European Journal of Cancer, 37, S27-28.
Specific cancer studies include: multiple myeloma, leukemia, glioblastoma, renal cancer, cancer cachexia and colorectal cancer.
[UKPRwire, Mon Jun 17 2019] This report on the cancer cachexia market analyzes the current and future scenario of the global market.
[USPRwire, Wed Jun 12 2019] This report on the cancer cachexia market analyzes the current and future scenario of the global market.
[ClickPress, Mon Jun 17 2019] This report on the cancer cachexia market analyzes the current and future scenario of the global market.

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