cannabinol


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cannabinol

[′kan·ə·bə‚nȯl]
(organic chemistry)
C21H26O2 A physiologically inactive phenol formed by spontaneous dehydrogenation of tetrahydrocannabinol from cannabis.
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[2] Nonstandard abbreviations: THC, A9-tetrahydrocannabinol; CYP, cytochrome P450; 11-OH-THC, 11-hydroxy-A9-tetrahydrocannabinol; THCCOOH, 11-nor-9-carboxy-A9-tetrahydrocannabinol; UGT, uridine 5'-diphospho-glucuronosyltransferase; DUID, driving under the influence of drugs; CBD, cannabidiol; CBN, cannabinol; LC-MS/MS, liquid chromatography-tandem mass spectrometry; LOQ, limit of quantification; HSD, honestly significant difference; BMI, body mass index; [C.sub.max], highest observed analyte concentration; [T.sub.max], observed time to [C.sub.max]; SPE, solid-phase extraction.
[3] Nonstandard abbreviations: THC, [[DELTA].sup.9]-tetrahydrocannabinol; OF, oral fluid; 11-OH-THC, 11-hydroxy-THC; THCCOOH, 11-nor-9-carboxy THC; DUID, driving under the influence of drugs; CBD, cannabidiol; CBN, cannabinol; 2D-GC-MS, 2-dimensional GC-MS; LOQ, limit of quantification; BMI, body mass index; SAMHSA, Substance Abuse and Mental Health Services Administration; DRUID, Driving under the Influence of Drugs, Alcohol and Medicines.
Participant Trimester of THC, 11-hydroxy- 8[beta], number last use (a) ng/g THC, ng/g 11-dihydroxy- THC, ng/g 12 3 46.6 13.2 20 3 18.1 12 23 3 105.5 27.9 29 3 44.3 34 3 37 1 38 3 20.6 39 3 19.0 41 3 16.0 45 2 52 3 60 3 39.8 13.2 61 b 62 3 66 2 72 3 26.9 45.8 73 3 74 1 76 3 78 2 No., positive 0 9 5 % 0 45 20 Median 26.9 13.2 Interquartile 18.6-45.5 12.6-36.9 range Participant THCCOOH, Cannabinol, number ng/g ng/g 12 459.6 46.6 20 164.3 40.8 23 443.5 186.0 29 245.2 79.5 34 22.7 37 13.7 38 136.3 19.3 39 29.7 15.9 41 54.8 45 17.0 12.2 52 13.3 60 270.5 23.9 61 17.2 62 39.5 66 107.3 72 43.9 12.1 73 21.9 74 18.7 76 15.4 12.5 78 48.1 10.6 No., positive 20 11 % 100 55 Median 41.7 19.3 Interquartile 17.6-157 12.2-46.6 range (a) As determined by maternal self-report and/or oral fluid testing.
Pharmacokinetics and metabolism of the plant cannabinoids, A9-tetrahydrocannabinol, cannabidiol and cannabinol. In: Pertwee RG, ed.
delta-9-tetrahycrocannabinol (THC), cannabigerol (CBG) and cannabinol
The new policy covers medicines which contain the drug described as containing "cannabis, cannabis resin, cannabinol or a cannabinol derivative".
On November 1, the go-ahead was given for products containing cannabis, cannabis resin or cannabinol, to be made available on prescription.
Consultants have been given the choice to prescribe products containing cannabis, cannabis resin or cannabinol, if they feel their patients could benefit from it.
These are that it "needs to be a preparation or product which contains cannabis, cannabis resin, cannabinol or a cannabinol derivative; it is produced for medicinal use in humans and; is a medicinal product, or a substance or preparation for use as an ingredient of, or in the production of an ingredient of, a medicinal product".
When questioned by prosecutors, the suspect was cited as admitting that he possessed and consumed drugs after tests had shown traces of tetra-hydro cannabinol (THC), an active component of hashish, was found in his system.
Delta-8-Tetrahydrocannabinol (8-THC) and Cannabinol (CBN) produce psychoactive effects in humans but with less intensity than 9-THC (Table 1) (De Souza, Karniol, and Ventura, 1974; Hollister and Gillespie, 1973; Karniol and Carlini, 1973; Perez-Reyes, 1973).
These include illegal possession of 72.9562 grams of cannabinol and ketamine; illegal possession of 67 grams of marijuana; 6.91 grams of MDMA-ecstasy; 3.67 grams of Clonazepam, a sedative-hypnotic party drug; 1.79 grams of cocaine; 0.8 grams of ketamine and 'shabu' or crystal meth; and eight grams more of meth and amphetamine.