cap-binding protein


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cap-binding protein

[¦kap ‚bīnd·iŋ ′prō‚tēn]
(cell and molecular biology)
A protein that specifically recognizes the methylated cap of eukaryotic messenger ribonucleic acid (mRNA) and is essential in the regulation of mRNA translation.
References in periodicals archive ?
The effects of the 5' cap in mRNA translation was studied extensively and soon it was found that most eukaryotic translation is initiated with a cap-binding protein (named later as eIF4E) that was identified by Sonenberg et al.
1988) Cap-binding proteins of eukaryotic mRNA: Functions in initiation and control of translation.
Translational control and metastatic progression: enhanced activity of the mRNA cap-binding protein eIF-4E selectively enhances translation of metastasis-related mRNAs.