Myopathy

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myopathy

[mī′äp·ə·thē]
(medicine)
Any disease of the muscles. Also known as myopathia.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Myopathy

 

progressive muscular dystrophy; a hereditary disease.

Myopathies can be transmitted as autosomal recessive or dominant, or sex chromosome-linked traits. Myopathies result from metabolic disturbances in muscle cells and a change in the biosynthesis of nucleic acids; the degradation of muscle proteins is considerably more rapid than their biosynthesis. In myopathies, muscles become flaccid and some of the fibers are replaced by fatty tissue. Electron microscopy reveals structural changes in the membranes of muscle cells. The main symptoms of the disease are increasing muscular weakness, symmetrical muscular atrophy, decrease in tendon reflexes and, in the later stages, bone and joint deformity. Autonomic trophic nerve functions are invariably impaired.

Myopathy is treated with anticholinesterase preparations, anabolic hormones, and vitamins B and E. Preventive measures include early diagnosis and detection of the heterozygous carrier state for the myopathy gene by using electrophysiological and biochemical tests.

REFERENCES

Badalian, L. O., V. A. Tabolin, and Iu. V. Vel’tishchev. Nasledstvennye bolezni u detei. Moscow, 1971.
Hausmanowa-Petrusewicz, I. Myshechnye zabolevaniia. Warsaw, 1971. (Translated from Polish.)

L. O. BADALIAN

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
In mammals, capture myopathy has been classified as a range of 4 different syndromes, each with its own unique etiology and pathogenesis, which ultimately result in muscle necrosis.
Risk factors for capture myopathy include stress, fear, overexertion, hyperthermia, and chronic vitamin E or selenium deficiency.
Birds with capture myopathy typically present with ataxia or generalized weakness.
Treatment of capture myopathy is complex because of the multifactorial nature of the disease.
(15,20,21) In the successful treatment of capture myopathy in sandhill cranes, assisting the birds to a standing position with a towel and allowing them to walk with that support provided the necessary rehabilitation for the animals to recover.
Because undue stress and fear are 2 of the most important components of capture myopathy, the excitable nature of wild and wild-caught birds exacerbates the symptoms of capture myopathy.
Although there have been empirical reports of flamingoes surviving capture myopathy, this is the first case, to our knowledge, where a detailed therapeutic plan in any flamingo species has been documented as succesful.