carbamoyl


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carbamoyl

[kär′bam·ə‚wil]
(organic chemistry)
The radical NH2CO, formed from carbamic acid.
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References in periodicals archive ?
Rayment, "Structure of carbamoyl phosphate synthetase: a journey of 96 a from substrate to product," Biochemistry, vol.
Accordingly compound 3 was prepared by the reaction of dimethyl carbamoyl chloride 2 with piperazine 1 in ratio 2: 1 using DCM as a solvent in the presence of 10% NaOH in water.
Synthesis of Ligand 2,5-Bis((4-bromophenyl) carbamoyl) Terephthalic Acid (1).
The benzamide derivatives, which are in clinical trials, are Entinostat (MS-275 or pyridin-3-yl methyl 4-((2-aminophenyl) carbamoyl) benzyl carbamate) currently in phase II clinical trial for Hodgkin lymphoma, phase I trial ofadvanced leukemia and myelodysplastic syndrome (MDS), and Mocetinostat (MGCD0103 or N-(2-Aminophenyl)-4[[(4- pyridin-3-ylpyrimidin-2-yl)amino]methyl] benzamide) in phase II clinical trial for Hodgkin lymphoma, phase I trial of advanced leukemia, myelodysplastic syndrome (MDS), diffuse large B-cell lymphoma, and follicular lymphoma [12-15].
Paralogous gene couples included elongation factors (e.g., EF-Tu and EFG), ATPases ([alpha] and [beta] subunits), signal recognition particle proteins, and carbamoyl phosphate synthetases, all believed to be very ancient (reviewed in [16]).
To overcome any serendipity, positive controls such as acetyl phosphate, carbamoyl phosphate, dihydroxyacetone-P, phosphoramidate, and monophosphoimidazole were used throughout the docking procedure.
Valproic acid inhibits the activity of carbamoyl phosphate synthetase I, the first enzymatic reaction in the urea cycle, thereby hindering the excretion of ammonia and raising plasma ammonia levels.
group for a carbamoyl group substitution in the polar tail.
Understanding carbamoyl phosphate synthetase deficiency: impact of clinical mutations on enzyme functionality.
Many synthetic organic compounds containing carbamoyl function are known to be biologically active and found to have medicinal [4] and agricultural [5] applications.
Carbamate-pesticides, oxamyl (methyl-2 (dimethylamine)-N-(methylamino) carbonyl) oxy) 2-oxoethanimidothioate (I) S-Ethyl-N-[(methyl carbamoyl oxy)]thioacetimidate (II) and N-Phenyl-(ethyl carbamoyl) propylcarbamate (III) are non-ionic pesticides and found suitable for effective control of nematodes and herbs.