carbonylation


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carbonylation

[kär‚bän·əl′ā·shən]
(chemistry)
Introduction of a carbonyl radical into a molecule.
References in periodicals archive ?
Protein carbonylation, cellular dysfunction, and disease progression.
McElwee-White, W(CO)6-Catalyzed Oxidative Carbonylation of Primary Amines to N, N'-Disubstituted Ureas in Single or Biphasic Solvent Systems.
Here, we confirmed that the livers of apoCIII mice have lower levels of GSH regardless of diet type, while consumption of a HFD induced protein carbonylation in the livers of both apoCIII and NTg mice.
Li and LXC mixture showed similar values to the control group in all markers, except for protein carbonylation. Regarding protein carbonylation, cells Li- and LXC-treated present.
Cell homogenates were incubated with the classical carbonyl reagent DNPH, and protein carbonylation was measured spectrophotometrically at 375 nm.
Moreover, it increased oxidative stress (decreased antioxidant enzyme activities and GSH/GSSG ratio, increased xanthine oxidase enzyme activity, lipid peroxidation, protein carbonylation and ROS generation) and enhanced the proinflammatory cytokines levels, activity of myeloperoxidase and nuclear translocation of NF[kappaB in the cardiac tissue of the experimental animals.
They include oxidation, racemization, isomerization, deamidation, nitration, carbonylation, carbamylation, and glycation (or glycoxidation) (1).
Chapters on specific small molecules cover topics including nitrogen monoxide and nitrous oxide binding and reduction, bio-organometallic approaches to nitrogen fixation chemistry, methane functionalization, catalytic hydrolysis, and carbonylation catalysis in the use of carbon monoxide as a chemical feedstock.
When the researchers bombarded radiation-resistant bacteria with gamma rays, manganese appeared to protect proteins from a form of oxidative damage called carbonylation. But in radiation-sensitive bacteria with little manganese, gamma rays caused high levels of protein oxidation, and the microbes died.
Monsanto's process for the carbonylation of methanol to acetic acid uses an extremely expensive (but highly efficient and recyclable) rhodium-containing catalyst in the presence of iodide.
Extreme or pathologic conditions generate much higher levels of ROS that overwhelm cellular antioxidant defenses, leading to protein carbonylation, DNA damage, and RNA oxidation.
Following UVA exposure, a significant increase in protein oxidation occurred, as evident from the darker and/or new protein bands compared to nonirradiated cells, while protein carbonylation levels in AMT-treated cells were less affected (Figure 4(b)).