carcinoma in situ


Also found in: Dictionary, Thesaurus, Medical, Acronyms, Wikipedia.
Related to carcinoma in situ: squamous cell carcinoma

carcinoma in situ

[‚kärs·ən′ō·mə in ′si·chü]
(medicine)
A malignant tumor in the premetastatic stage, when cells are at the site of origin.
References in periodicals archive ?
Atypical lobular hyperplasia and lobular carcinoma in situ without other high-risk lesions diagnosed on vacuum-assisted core needle biopsy: the problem of excisional biopsy.
The natural history of low-grade ductal carcinoma in situ of the breast in women treated by biopsy only revealed over 30 years of longterm follow-up.
The VISTA Trial is an open-label, multicenter, single-arm Phase 3 clinical trial evaluating the efficacy and tolerability of Vicinium in patients with high-grade non-muscle invasive bladder cancer (NMIBC) that is Carcinoma in situ, which is cancer found on the inner lining of the bladder that has not spread into muscle or other tissue and/or papillary, which is cancer that has grown from the bladder lining out into the bladder but has not spread into muscle or other tissue, who have been previously treated with bacillus Calmette-Guerin.
Predictors of recurrence for ductal carcinoma in situ after breast-conserving surgery.
Jirstrom et al., "The prognostic role of HER2 expression in ductal breast carcinoma in situ (DCIS); A Population-Based Cohort Study," BMC Cancer, vol.
Julian et al., "Anastrozole versus tamoxifen in postmenopausal women with ductal carcinoma in situ undergoing lumpectomy plus radiotherapy (NSABP B-35): a randomised, double-blind, phase 3 clinical trial," The Lancet, vol.
We observed a significant decrease in E-cadherin membrane expression from dysplasia to carcinoma in situ to invasive carcinoma and a significant increase in vimentin expression with progression of the tumor.
As an unintended consequence, screening for invasive breast cancer has resulted in a marked increase in the diagnosis of asymptomatic ductal carcinoma in situ. The majority of women diagnosed with screen-detected DCIS are not destined to relapse or die of their disease.
Kane, "Ductal carcinoma in Situ of the breast: a systematic review of incidence, treatment, and outcomes," Journal of the National Cancer Institute, vol.
In one example, they say that some premalignant conditions, like one that affects the breast called ductal carcinoma in situ -- which many doctors agree is not cancer -- should be renamed to exclude the word carcinoma.
The incidence of breast carcinoma in situ is increasing, yet poorly understood.