Cachexia

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Related to cardiac cachexia: Cardiac catheterization

cachexia

[ka′kek·sē·ə]
(medicine)
Weight loss, weakness, and wasting of the body encountered in certain diseases or in terminal illnesses.

Cachexia

 

a state of profound wasting and physical debility manifested by severe emaciation, weight loss, dry and flabby skin, loss of hair, disappearance of subcutaneous fat, atrophy of muscles and viscera, and low serum protein level. Edema, hemorrhages, and sometimes mental derangement can occur with cachexia. It results from prolonged malnutrition or starvation, severe metabolic disorders, chronic arsenic, lead, mercury, or fluorine poisoning, and severe lesions of the digestive tract (atrophy of the intestinal mucosa, condition after resection of the stomach and intestines). Cachexia may occur in severe cases of tuberculosis or other chronic infections, some lesions of the endocrine glands, (hypophysis, thyroid, adrenals, pancreas), large slow-healing wounds, abscesses, and malignant tumors (especially of the esophagus and stomach).

References in periodicals archive ?
Molecular mechanisms and signaling pathways of angiotensin II-induced muscle wasting: potential therapeutic targets for cardiac cachexia," The International Journal of Biochemistry & Cell Biology, vol.
It is important to highlight that these multiple direct and indirect mechanisms involving Ang II-induced muscle wasting are potential mediators of cardiac cachexia.
Gastro-intestinal protein loss is likely to be rare in patients with cardiac cachexia and is therefore not a significant factor in its production.
Cecchini, "Oxidative and proteolytic profiles of the right and left heart in a model of cancer-induced cardiac cachexia," Pathophysiology, vol.
An understanding of the underlying mechanisms of cardiac cachexia may allow the treatment of CHF and undernutrition independently thereby reducing the excessive morbidity and mortality associated with this condition.
Fat malabsorption has been implicated in the development of cardiac cachexia [12-14] but the relevant studies were poorly designed and uncertainty still exists about the role of fat malabsorption in cardiac cachexia.
Clinical characteristics of patients with heart failure CC NON-CC (n = 29) (n = 14) Severity of heart failure NYHA II 9 8 III 15 6 IV 5 0 Rhythm SR 9 5 AF 20 9 Orthopnoea(*) Yes 27 4 No 2 10 Early satiety(**) Yes 20 2 No 9 12 Anorexia(***) Yes 13 1 No 16 13 CC = cardiac cachexia group; NON-CC = patients without cachexia.
2] exhalations (%) in the triolein (TBT) and glycocholic acid (GABT) breath tests [mean (SD)] in controls, and heart failure patients with (CC) and without (NON-CC) cardiac cachexia Controls CC NON-CC (n = 29) (n = 29) (n = 14) TBT(**) 12.