Cardiovascular signs originate due to the activity of the cardiac glycosides
. Their mechanism of action is based on the inhibition of sodium-potassium pump (Na/K-ATPase), resulting in depletion of intracellular potassium and increased level of intracellular sodium.
In Pleurotus spp2 Tannin, phlobatannins and Terpenoids were absent in paddy straw substrates but shows the presence of saponin, flavonoids, steroids but absences of saponin, Terpenoids and cardiac glycosides
. Phlobatannins were present in the sugarcane trash substrates but absent in all other substrates, paddy straw, teak leaves, black gram pods and banana leaves.
Detection of cardiac glycosides
(Keller Killiani's Test)
Acute yellow oleander (Thevetia peruviana) poisoning: cardiac arrhythmias, electrolyte disturbances, and serum cardiac glycoside
concentrations on presentation to hospital.
Milky wax exuding from the stem contains cardiac glycosides
(calotropin, uscharin) and fatty acids.
The results obtained from the phytochemical screening of the extract in Table 1 agrees with those reported by Ogundare and Onifade (2009) and Patience and Godwin (2010) which stated that phenolics, alkaloids, cardiac glycosides
, flavonoids, terpenoids, and steroids are present in the methanolic extract of A.
Otung, 1991.Microbiological exploitation of cardiac glycosides
and alkaloids from Garcinia kola, Borreriao cymoides, Kola nitida and Citrus aurantifolia.
Hypothesis: It was previously reported that Cardiac glycosides
possessed antitumor activity by inducing apoptosis of multiple cancer cells through oxidative stress.
First described in 1785 by William Withering, cardiac glycosides
have been used in the treatment of heart failure for > 200 years,  and digoxin had been the most commonly used of these compounds.
The cardiac glycosides
therapeutically have the capability to enhance the power of the heart beat without any increase in the amount of oxygen required by the heart muscle.
(3,4) Contrary to cardiac glycosides
, and most intravenous and oral inotropes, pimobendan does not increase myocardial oxygen consumption.
The aqueous extract of green tea was subjected to qualitative analysis for the following organic plant constituents: alkaloids, proteins amino acids, anthraquinones, flavonoids, carbohydrates, saponins, tannins, steroids, triterpenoids, and cardiac glycosides
[10,11] (Table 1).