AFE is traditionally diagnosed clinically, in a woman early during labor with ruptured membranes, by a trio of symptoms: acute respiratory distress, cardiovascular collapse
, and coagulopathy [3-5, 8, 9, 11].
RMS is characterised by pruritis, and erythematous rash involving face, neck and upper torso, upper body flushing, hypotension, and cardiovascular collapse
.  Patients develop these signs and symptoms 4-10 min after starting infusion or may begin after its completion.
Pregnant PAH women die of Heart failure and cardiovascular collapse
. Majority of the deaths are noted in early postpartum period.
Traditionally, the presenting signs include a combination of altered mentation (agitation, confusion, and unresponsiveness), apnea, cardiovascular collapse
(hypotension, bradycardia, or asystole), and shivering in association with ophthalmoplegia and amaurosis in the contralateral eye.
Alpha-blocker treatment has been considered contraindicated for dopamine secreting pheochromocytomas because case reports have shown it can lead to cardiovascular collapse
and potential hypotensive crisis .
If it is prolonged, it can lead to asystole, and, ultimately, cardiovascular collapse
may occur, especially in patients with severe coronary artery disease and stenosed valves.
(4) Following the excessive intake of CCB and BB drugs, treatments, such as glucagon, calcium gluconate, and hyperinsulinemic euglycemia therapy (HIET) as well as vasopressor drugs and intravenous fluid therapy are used in cases with cardiovascular collapse
. (5) Lately, in CCB and BB poisonings unresponsive to standard therapy, Recently, intravenous lipid infusion (ILI) therapy, which is used for poisoning with lipophilic local anesthetics and chemical agents, is a new therapy option when the standard therapy is inefective for poisoning with CCB and BB intoxications.
Chronic lung vessel damage and inflammation lead to a condition known as pulmonary hypertension, which can lead to heart failure and an increased risk of blood clot formation resulting in a sudden blockage of blood flow causing cardiovascular collapse
The cardiac effects of excessive intake are myocardial depression, cardiovascular collapse
, heart block, bradycardia, vasodilatation (relative volume deficit), and hypotension.
Levobupivacaine-induced seizures and cardiovascular collapse
treated with Intralipid.
Management must be immediate, because anaphylaxis is life threatening and may produce cardiovascular collapse
. It consists of withdrawing the offending drug, interrupting the effects of the preformed mediators that were released in response to the antigen, and preventing more mediator release.