Health effects from exposure to chemicals found in burn pits may include cancer, neurological effects, reproductive effects, respiratory toxicity, and cardiovascular toxicity
With longer survival, cancer patients are now subject to the cardiovascular effects of aging as well as potential cardiovascular toxicity
from modern cancer agents.
As reported previously, the FDA now requires that all new drugs approved for diabetes rule out cardiovascular toxicity
rather than simply showing the agent lowers HbA1c levels.
Cardiac toxicity of local anesthetics: Cardiovascular toxicity
produces changes in cardiac conduction, impairment of contractility and myocardial metabolic changes.
The reality is that trastuzumab is an effective medicine for treating breast cancer, but the risk of cardiovascular toxicity
is underrated, explains Juan Carlos Plana, MD, co-director of Cleveland Clinic's Cardio-Oncology Center.
1 It's clear that cardiovascular toxicity
occurs more frequently than hepatoxicity.
Kim JT, Jung CW, Lee KH 2004 The effect of insulin on the resuscitation of bupivacaine-induced severe cardiovascular toxicity
in dogs Anesthesia & Analgesia 99 (3) 728-33
1136) assessed the impacts of load-related differences in DEE composition on models of inflammation, susceptibility to infection, and cardiovascular toxicity
The administration of epinephrine at high doses (animal models) during the resuscitation maneuvers, together with Lipid Emulsions (LE) for managing cardiovascular toxicity
due to bupivacaine, showed no benefits in recovery and suggests that this combination will prevent the reversal of bupivacaine toxicity (35).
of Selected Chemotherapy Agents Acute Coronary Heart Failure Hypertension Syndromes QTc Prolongation Anthracyclines Bevacizumab Fluorouracil Arsenic trioxide Trastuzumab Sorafenib Bevacizumab Depsipeptide Lapatinib Sunitinib Sorafenib Sunitinib Alemtuzumab VDAs * VDAs Dasatinib VDAs * Vascular disrupting agents Source: Dr.
The potential cardiovascular toxicity
of these dementia drugs may be under-appreciated by clinicians, Park-Wyllie adds.
The search for less toxic, long-acting LAs was prompted by fatalities associated with the cardiovascular toxicity