caspase


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Related to caspase: Caspase 3, Caspase 9

caspase

[′kas‚pās]
(cell and molecular biology)
Any of a family of intracellular proteins that mediate apoptosis.
References in periodicals archive ?
Apoptotic protein expression and activation of caspases is changed following cholinergic denervation and hippocampal sympathetic in growth in rat hippocampus.
Furthermore, weak brown-colored MCF7 cells were observed by tiliroside 50 [micro]g/ml from the expression of Caspase 8.
Improved detection of apoptotic cells in archival paraffin sections: Immunohistochemistry using antibodies to cleaved caspase 3.
A lot of Ehrlich carcinoma cells expressed both p53 & Caspase 3 and present predominantly in large blood vessels central veins and less in sinusoids and periportal areas.
Maruyama, "Attenuation of ischemia/reperfusion injury in rats by a caspase inhibitor," Circulation, vol.
The extrinsic pathway is triggered when death ligands bind to their respective cell surface death receptors through recruitment of FAS-associated death domain (FADD) protein, procaspase-8 through the formation of a complex that induces cell death and activation of the caspases (caspase-8 and caspase-10).
To assess the activation of caspase 3, 8, 9 in EBV-mediated apoptosis, cells were treated with EBV for up to 7 days.
Levels of caspase protein made by the dying coral shot up to six times normal levels, while levels of the protein dropped in the heat-resistant coral.
It also exerts its proapoptotic function via its protease activity, independent of IAP and caspase.
From the SCOP database it was found that all the caspase-3 proteins belongs to alpha and beta proteins and they are in the caspase catalytic domain family.
In tests with primary T cells or Jurkat T leukemia cells, the extended presence of YopH led to apoptosis through a mitochondria-dependent pathway, as indicated by mitochondrial breakdown, caspase activation, DNA fragmentation, and annexin V binding.

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